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Early ecological changes in intestinal microbiota with the long-acting GLP-2 analog apraglutide in short bowel syndrome.

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Title: Early ecological changes in intestinal microbiota with the long-acting GLP-2 analog apraglutide in short bowel syndrome.
Authors: Ekhlas D; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium., Verbiest A; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium., Stas M; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium., De Meyere L; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium., Vandermeulen G; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium., Tóth J; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium., Geboers K; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium., Timmermans L; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium., Verspecht C; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium., Wauters L; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium., Vermeersch P; Clinical Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium., Jeppesen PB; Department of Intestinal Failure and Liver Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Verbeke K; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium., Joly F; Centre for Intestinal Failure, Department of Gastroenterology and Nutritional Support, Hôpital Beaujon, Clichy, University of Paris, INSERM UMR 1149, France., Derrien M; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium., Raes J; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium., Vanuytsel T; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium. Electronic address: tim.vanuytsel@uzleuven.be.
Source: Clinical nutrition ESPEN [Clin Nutr ESPEN] 2026 Jun; Vol. 73, pp. 103138. Date of Electronic Publication: 2026 Mar 26.
Publication Type: Journal Article; Multicenter Study; Clinical Trial, Phase II
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101654592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-4577 (Electronic) Linking ISSN: 24054577 NLM ISO Abbreviation: Clin Nutr ESPEN Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2405-4577
DOI:10.1016/j.clnesp.2026.103138