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Early ecological changes in intestinal microbiota with the long-acting GLP-2 analog apraglutide in short bowel syndrome.

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Title: Early ecological changes in intestinal microbiota with the long-acting GLP-2 analog apraglutide in short bowel syndrome.
Authors: Ekhlas D; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium., Verbiest A; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium., Stas M; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium., De Meyere L; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium., Vandermeulen G; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium., Tóth J; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium., Geboers K; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium., Timmermans L; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium., Verspecht C; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium., Wauters L; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium., Vermeersch P; Clinical Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium., Jeppesen PB; Department of Intestinal Failure and Liver Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Verbeke K; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium., Joly F; Centre for Intestinal Failure, Department of Gastroenterology and Nutritional Support, Hôpital Beaujon, Clichy, University of Paris, INSERM UMR 1149, France., Derrien M; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium., Raes J; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium., Vanuytsel T; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium. Electronic address: tim.vanuytsel@uzleuven.be.
Source: Clinical nutrition ESPEN [Clin Nutr ESPEN] 2026 Jun; Vol. 73, pp. 103138. Date of Electronic Publication: 2026 Mar 26.
Publication Type: Journal Article; Multicenter Study; Clinical Trial, Phase II
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101654592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-4577 (Electronic) Linking ISSN: 24054577 NLM ISO Abbreviation: Clin Nutr ESPEN Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Early ecological changes in intestinal microbiota with the long-acting GLP-2 analog apraglutide in short bowel syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Ekhlas+D%22">Ekhlas D</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Verbiest+A%22">Verbiest A</searchLink>; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Stas+M%22">Stas M</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Meyere+L%22">De Meyere L</searchLink>; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vandermeulen+G%22">Vandermeulen G</searchLink>; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Tóth+J%22">Tóth J</searchLink>; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Geboers+K%22">Geboers K</searchLink>; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Timmermans+L%22">Timmermans L</searchLink>; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Verspecht+C%22">Verspecht C</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Wauters+L%22">Wauters L</searchLink>; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vermeersch+P%22">Vermeersch P</searchLink>; Clinical Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Jeppesen+PB%22">Jeppesen PB</searchLink>; Department of Intestinal Failure and Liver Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Verbeke+K%22">Verbeke K</searchLink>; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Joly+F%22">Joly F</searchLink>; Centre for Intestinal Failure, Department of Gastroenterology and Nutritional Support, Hôpital Beaujon, Clichy, University of Paris, INSERM UMR 1149, France.<br /><searchLink fieldCode="AU" term="%22Derrien+M%22">Derrien M</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Raes+J%22">Raes J</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KULeuven, Leuven, Belgium; Centre for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vanuytsel+T%22">Vanuytsel T</searchLink>; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMeta), KULeuven, Leuven, Belgium; Leuven Intestinal Failure and Transplantation Centre (LIFT), University Hospitals Leuven, Leuven, Belgium. Electronic address: tim.vanuytsel@uzleuven.be.
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  Data: <searchLink fieldCode="JN" term="%22101654592%22">Clinical nutrition ESPEN</searchLink> [Clin Nutr ESPEN] 2026 Jun; Vol. 73, pp. 103138. <i>Date of Electronic Publication: </i>2026 Mar 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ltd%22">Elsevier Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101654592 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2405-4577 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224054577%22">24054577 </searchLink><i>NLM ISO Abbreviation: </i>Clin Nutr ESPEN <i>Subsets: </i>MEDLINE
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