A prospective multicenter randomized controlled trial pre-emptive increase in immunosuppression for asymptomatic serological reactivation in patients with lupus nephritis in clinical remission.

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Title: A prospective multicenter randomized controlled trial pre-emptive increase in immunosuppression for asymptomatic serological reactivation in patients with lupus nephritis in clinical remission.
Authors: Yap DYH; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Chan SCW; Division of Rheumatology and Clinical Immunology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Wong PYH; Renal Unit, Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong SAR, China., Wong S; Renal Unit, Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong SAR, China., Zhang D; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Yung S; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Lo JMW; Renal Unit, Department of Medicine and Geriatrics, Kwong Wah Hospital, Hong Kong SAR, China., Lau CS; Division of Rheumatology and Clinical Immunology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Tang C; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Chan TM; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China. Electronic address: dtmchan@hku.hk.
Source: Kidney international [Kidney Int] 2026 Jul; Vol. 110 (1), pp. 245-254. Date of Electronic Publication: 2026 Mar 27.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Comparative Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1755 (Electronic) Linking ISSN: 00852538 NLM ISO Abbreviation: Kidney Int Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1523-1755
DOI:10.1016/j.kint.2026.02.037