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A prospective multicenter randomized controlled trial pre-emptive increase in immunosuppression for asymptomatic serological reactivation in patients with lupus nephritis in clinical remission.

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Title: A prospective multicenter randomized controlled trial pre-emptive increase in immunosuppression for asymptomatic serological reactivation in patients with lupus nephritis in clinical remission.
Authors: Yap DYH; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Chan SCW; Division of Rheumatology and Clinical Immunology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Wong PYH; Renal Unit, Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong SAR, China., Wong S; Renal Unit, Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong SAR, China., Zhang D; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Yung S; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Lo JMW; Renal Unit, Department of Medicine and Geriatrics, Kwong Wah Hospital, Hong Kong SAR, China., Lau CS; Division of Rheumatology and Clinical Immunology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Tang C; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Chan TM; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China. Electronic address: dtmchan@hku.hk.
Source: Kidney international [Kidney Int] 2026 Jul; Vol. 110 (1), pp. 245-254. Date of Electronic Publication: 2026 Mar 27.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Comparative Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1755 (Electronic) Linking ISSN: 00852538 NLM ISO Abbreviation: Kidney Int Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A prospective multicenter randomized controlled trial pre-emptive increase in immunosuppression for asymptomatic serological reactivation in patients with lupus nephritis in clinical remission.
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  Data: <searchLink fieldCode="AU" term="%22Yap+DYH%22">Yap DYH</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chan+SCW%22">Chan SCW</searchLink>; Division of Rheumatology and Clinical Immunology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Wong+PYH%22">Wong PYH</searchLink>; Renal Unit, Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Wong+S%22">Wong S</searchLink>; Renal Unit, Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Zhang+D%22">Zhang D</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Yung+S%22">Yung S</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Lo+JMW%22">Lo JMW</searchLink>; Renal Unit, Department of Medicine and Geriatrics, Kwong Wah Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Lau+CS%22">Lau CS</searchLink>; Division of Rheumatology and Clinical Immunology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Tang+C%22">Tang C</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chan+TM%22">Chan TM</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China. Electronic address: dtmchan@hku.hk.
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  Data: <searchLink fieldCode="JN" term="%220323470%22">Kidney international</searchLink> [Kidney Int] 2026 Jul; Vol. 110 (1), pp. 245-254. <i>Date of Electronic Publication: </i>2026 Mar 27.
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  Data: Journal Article; Randomized Controlled Trial; Multicenter Study; Comparative Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0323470 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1523-1755 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200852538%22">00852538 </searchLink><i>NLM ISO Abbreviation: </i>Kidney Int <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.kint.2026.02.037
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      – Code: eng
        Text: English
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        StartPage: 245
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      – TitleFull: A prospective multicenter randomized controlled trial pre-emptive increase in immunosuppression for asymptomatic serological reactivation in patients with lupus nephritis in clinical remission.
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              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
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