A new murine gram-negative sepsis model with standard care satisfies Sepsis-3 and reproduces clinical pathology.

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Title: A new murine gram-negative sepsis model with standard care satisfies Sepsis-3 and reproduces clinical pathology.
Authors: Bastow CR; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Mei C; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Wen SW; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Wilson JL; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Nguyen H; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Suthya AR; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Bourne JH; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Lankadeva YR; Translational Cardiovascular and Renal Research Group, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia.; Department of Critical Care, Melbourne Medical School, The University of Melbourne, Melbourne, VIC, Australia.; Department of Anaesthesia, Austin Hospital, Melbourne, VIC, Australia., Wong CHY; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia. connie.wong@monash.edu.
Source: Intensive care medicine experimental [Intensive Care Med Exp] 2026 Mar 30; Vol. 14 (1). Date of Electronic Publication: 2026 Mar 30.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag, GmbH Country of Publication: Germany NLM ID: 101645149 Publication Model: Electronic Cited Medium: Print ISSN: 2197-425X (Print) Linking ISSN: 2197425X NLM ISO Abbreviation: Intensive Care Med Exp Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:2197-425X
DOI:10.1186/s40635-026-00886-5