A new murine gram-negative sepsis model with standard care satisfies Sepsis-3 and reproduces clinical pathology.

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Title: A new murine gram-negative sepsis model with standard care satisfies Sepsis-3 and reproduces clinical pathology.
Authors: Bastow CR; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Mei C; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Wen SW; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Wilson JL; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Nguyen H; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Suthya AR; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Bourne JH; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Lankadeva YR; Translational Cardiovascular and Renal Research Group, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia.; Department of Critical Care, Melbourne Medical School, The University of Melbourne, Melbourne, VIC, Australia.; Department of Anaesthesia, Austin Hospital, Melbourne, VIC, Australia., Wong CHY; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia. connie.wong@monash.edu.
Source: Intensive care medicine experimental [Intensive Care Med Exp] 2026 Mar 30; Vol. 14 (1). Date of Electronic Publication: 2026 Mar 30.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag, GmbH Country of Publication: Germany NLM ID: 101645149 Publication Model: Electronic Cited Medium: Print ISSN: 2197-425X (Print) Linking ISSN: 2197425X NLM ISO Abbreviation: Intensive Care Med Exp Subsets: PubMed not MEDLINE
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  Data: A new murine gram-negative sepsis model with standard care satisfies Sepsis-3 and reproduces clinical pathology.
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  Data: <searchLink fieldCode="AU" term="%22Bastow+CR%22">Bastow CR</searchLink>; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Mei+C%22">Mei C</searchLink>; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Wen+SW%22">Wen SW</searchLink>; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Wilson+JL%22">Wilson JL</searchLink>; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Nguyen+H%22">Nguyen H</searchLink>; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Suthya+AR%22">Suthya AR</searchLink>; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Bourne+JH%22">Bourne JH</searchLink>; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Lankadeva+YR%22">Lankadeva YR</searchLink>; Translational Cardiovascular and Renal Research Group, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia.; Department of Critical Care, Melbourne Medical School, The University of Melbourne, Melbourne, VIC, Australia.; Department of Anaesthesia, Austin Hospital, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Wong+CHY%22">Wong CHY</searchLink>; Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia. connie.wong@monash.edu.
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  Data: <searchLink fieldCode="JN" term="%22101645149%22">Intensive care medicine experimental</searchLink> [Intensive Care Med Exp] 2026 Mar 30; Vol. 14 (1). <i>Date of Electronic Publication: </i>2026 Mar 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%2C+GmbH%22">Springer-Verlag, GmbH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101645149 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2197-425X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222197425X%22">2197425X </searchLink><i>NLM ISO Abbreviation: </i>Intensive Care Med Exp <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41910926
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        Value: 10.1186/s40635-026-00886-5
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      – Code: eng
        Text: English
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              Text: 2026 Mar 30
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