Lack of Cerebrospinal Fluid α-Synuclein Seeding in VPS35 D620N- and LRRK2 Y1699C-Linked Parkinson's Disease.

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Title: Lack of Cerebrospinal Fluid α-Synuclein Seeding in VPS35 D620N- and LRRK2 Y1699C-Linked Parkinson's Disease.
Authors: Santinelli L; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany., Pratuseviciute N; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Lange LM; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.; Section for Movement Disorders, Department of Neurology, University of Lübeck, Lübeck, Germany.; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA., Kleinz T; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.; Section for Movement Disorders, Department of Neurology, University of Lübeck, Lübeck, Germany., Brüggemann N; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.; Section for Movement Disorders, Department of Neurology, University of Lübeck, Lübeck, Germany., Streubel-Gallasch L; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany., Möller M; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.; Section for Movement Disorders, Department of Neurology, University of Lübeck, Lübeck, Germany., Zimprich A; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Vienna, Austria.; Department of Neurology, Medical University Vienna, Vienna, Austria., Brücke C; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Vienna, Austria.; Department of Neurology, Medical University Vienna, Vienna, Austria., Good JM; Division of Genetic Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Griebner N; Section for Movement Disorders, Department of Neurology, University of Lübeck, Lübeck, Germany., Padmanabhan S; The Michael J. Fox Foundation for Parkinson's Research, New York, New York, USA., Seibler P; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany., Bauer P; CENTOGENE GmbH, Rostock, Germany.; Pomeranian Medical University, Szczecin, Poland., Vandenberghe W; Laboratory for Parkinson Research, Department of Neurosciences, Leuven, Belgium.; Department of Neurology, University Hospitals Leuven, Leuven, Belgium., Sammler E; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom., Blauwendraat C; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.; National Institutes of Health, Center for Alzheimer's and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA., Klein C; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany., Borsche M; Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.; Section for Movement Disorders, Department of Neurology, University of Lübeck, Lübeck, Germany.
Source: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2026 Jun; Vol. 41 (6), pp. 1605-1608. Date of Electronic Publication: 2026 Mar 30.
Publication Type: Letter
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8610688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8257 (Electronic) Linking ISSN: 08853185 NLM ISO Abbreviation: Mov Disord Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:1531-8257
DOI:10.1002/mds.70291