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The cGAS-STING pathway in senescence and aging-related diseases: mechanisms and therapeutic opportunities.

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Title: The cGAS-STING pathway in senescence and aging-related diseases: mechanisms and therapeutic opportunities.
Authors: Tan S; College of Life Science, Yangtze University, Jingzhou, 434025, China., Nepovimova E; Department of Chemistry, Faculty of Science, University of Hradec Králové, 500 03, Hradec Králové, Czech Republic.; Center of Advanced Innovation Technologies, VSB-Technical University of Ostrava, 70800, Ostrava-Poruba, Czech Republic., Valko M; Faculty of Chemical and Food Technology, Slovak University of Technology, 812 37, Bratislava, Slovakia., Jomova K; Department of Chemistry, Faculty of Natural Sciences, Constantine the Philosopher University in Nitra, Nitra, 949 74, Slovakia., Wu Q; College of Life Science, Yangtze University, Jingzhou, 434025, China. wqh212@hotmail.com., Kuca K; Center of Advanced Innovation Technologies, VSB-Technical University of Ostrava, 70800, Ostrava-Poruba, Czech Republic. kamil.kuca@uhk.cz.; Faculty of Informatics and Management, University of Hradec Kralove, 500 03, Hradec Kralove, Czech Republic. kamil.kuca@uhk.cz.; Biomedical Research Center, University Hospital Hradec Kralove, 50005, Hradec Kralove, Czech Republic. kamil.kuca@uhk.cz.
Source: Cell communication and signaling : CCS [Cell Commun Signal] 2026 Apr 01; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1478-811X
DOI:10.1186/s12964-026-02855-7