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The cGAS-STING pathway in senescence and aging-related diseases: mechanisms and therapeutic opportunities.

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Title: The cGAS-STING pathway in senescence and aging-related diseases: mechanisms and therapeutic opportunities.
Authors: Tan S; College of Life Science, Yangtze University, Jingzhou, 434025, China., Nepovimova E; Department of Chemistry, Faculty of Science, University of Hradec Králové, 500 03, Hradec Králové, Czech Republic.; Center of Advanced Innovation Technologies, VSB-Technical University of Ostrava, 70800, Ostrava-Poruba, Czech Republic., Valko M; Faculty of Chemical and Food Technology, Slovak University of Technology, 812 37, Bratislava, Slovakia., Jomova K; Department of Chemistry, Faculty of Natural Sciences, Constantine the Philosopher University in Nitra, Nitra, 949 74, Slovakia., Wu Q; College of Life Science, Yangtze University, Jingzhou, 434025, China. wqh212@hotmail.com., Kuca K; Center of Advanced Innovation Technologies, VSB-Technical University of Ostrava, 70800, Ostrava-Poruba, Czech Republic. kamil.kuca@uhk.cz.; Faculty of Informatics and Management, University of Hradec Kralove, 500 03, Hradec Kralove, Czech Republic. kamil.kuca@uhk.cz.; Biomedical Research Center, University Hospital Hradec Kralove, 50005, Hradec Kralove, Czech Republic. kamil.kuca@uhk.cz.
Source: Cell communication and signaling : CCS [Cell Commun Signal] 2026 Apr 01; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The cGAS-STING pathway in senescence and aging-related diseases: mechanisms and therapeutic opportunities.
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  Data: <searchLink fieldCode="AU" term="%22Tan+S%22">Tan S</searchLink>; College of Life Science, Yangtze University, Jingzhou, 434025, China.<br /><searchLink fieldCode="AU" term="%22Nepovimova+E%22">Nepovimova E</searchLink>; Department of Chemistry, Faculty of Science, University of Hradec Králové, 500 03, Hradec Králové, Czech Republic.; Center of Advanced Innovation Technologies, VSB-Technical University of Ostrava, 70800, Ostrava-Poruba, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Valko+M%22">Valko M</searchLink>; Faculty of Chemical and Food Technology, Slovak University of Technology, 812 37, Bratislava, Slovakia.<br /><searchLink fieldCode="AU" term="%22Jomova+K%22">Jomova K</searchLink>; Department of Chemistry, Faculty of Natural Sciences, Constantine the Philosopher University in Nitra, Nitra, 949 74, Slovakia.<br /><searchLink fieldCode="AU" term="%22Wu+Q%22">Wu Q</searchLink>; College of Life Science, Yangtze University, Jingzhou, 434025, China. wqh212@hotmail.com.<br /><searchLink fieldCode="AU" term="%22Kuca+K%22">Kuca K</searchLink>; Center of Advanced Innovation Technologies, VSB-Technical University of Ostrava, 70800, Ostrava-Poruba, Czech Republic. kamil.kuca@uhk.cz.; Faculty of Informatics and Management, University of Hradec Kralove, 500 03, Hradec Kralove, Czech Republic. kamil.kuca@uhk.cz.; Biomedical Research Center, University Hospital Hradec Kralove, 50005, Hradec Kralove, Czech Republic. kamil.kuca@uhk.cz.
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  Data: <searchLink fieldCode="JN" term="%22101170464%22">Cell communication and signaling : CCS</searchLink> [Cell Commun Signal] 2026 Apr 01; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Apr 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101170464 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1478-811X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221478811X%22">1478811X </searchLink><i>NLM ISO Abbreviation: </i>Cell Commun Signal <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12964-026-02855-7
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              Text: 2026 Apr 01
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