S-equol promotes ferroptosis in triple negative breast cancer by coordinating NCOA4-mediated ferritinophagy and PPARγ-mediated lipid metabolism.

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Title: S-equol promotes ferroptosis in triple negative breast cancer by coordinating NCOA4-mediated ferritinophagy and PPARγ-mediated lipid metabolism.
Authors: Ni F; Department of Breast Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China., Huang Z; Department of Breast Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China., Cui Y; Department of Gastrointestinal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China., Huang P; The Second School of Medicine, Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China., Xue Z; Department of Breast Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China., Huang G; School of Mental Health, Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China. huangguiqian@wmu.edu.cn., Zhao Y; Department of Breast Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China. zyx@wmu.edu.cn.
Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2026 May; Vol. 481 (5), pp. 2119-2137. Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-4919
DOI:10.1007/s11010-026-05524-y