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Discovery of Donor-Derived Exosomal DNA as an Exploratory Biomarker of Kidney Graft Rejection: A Cross-Sectional Study.

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Title: Discovery of Donor-Derived Exosomal DNA as an Exploratory Biomarker of Kidney Graft Rejection: A Cross-Sectional Study.
Authors: Cuadrado-Payán E; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain.; Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain., Ramírez-Bajo MJ; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain.; Red de Investigación Renal (REDINREN) and RICORS2040, Instituto de Salud Carlos III, Madrid, Spain., Banón-Maneus E; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain.; Red de Investigación Renal (REDINREN) and RICORS2040, Instituto de Salud Carlos III, Madrid, Spain., Rovira J; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain.; Red de Investigación Renal (REDINREN) and RICORS2040, Instituto de Salud Carlos III, Madrid, Spain., Hierro N; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain., Serrano-Jorcano D; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain., Argudo M; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain., Montagud-Marrahi E; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain., Rodríguez-Espinosa D; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain., Arana C; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain., Molina-Andújar A; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain., González-Rojas A; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain., Esforzado N; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain., Torregrosa V; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain., Ventura-Aguiar P; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain.; Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain., Broseta JJ; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain.; Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.; Red de Investigación Renal (REDINREN) and RICORS2040, Instituto de Salud Carlos III, Madrid, Spain., González-Roca E; CORE Molecular Biology Laboratory, Biomedical Diagnostic Center (CBD), Hospital Clínic Barcelona, Barcelona, Spain., Palou E; Department of Immunology, Hospital Clínic Barcelona, Barcelona, Spain., Diekmann F; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain.; Red de Investigación Renal (REDINREN) and RICORS2040, Instituto de Salud Carlos III, Madrid, Spain.; Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain., Cucchiari D; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain.; Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.; Red de Investigación Renal (REDINREN) and RICORS2040, Instituto de Salud Carlos III, Madrid, Spain., Revuelta I; Department of Nephrology and Kidney Transplantation, Hospital Clínic Barcelona, Barcelona, Spain.; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), Barcelona, Spain.; Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.; Red de Investigación Renal (REDINREN) and RICORS2040, Instituto de Salud Carlos III, Madrid, Spain.
Source: Transplant international : official journal of the European Society for Organ Transplantation [Transpl Int] 2026 Mar 18; Vol. 39, pp. 16061. Date of Electronic Publication: 2026 Mar 18 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S. A Country of Publication: Switzerland NLM ID: 8908516 Publication Model: eCollection Cited Medium: Internet ISSN: 1432-2277 (Electronic) Linking ISSN: 09340874 NLM ISO Abbreviation: Transpl Int Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1432-2277
DOI:10.3389/ti.2026.16061