View in EDS HTML Full Text PDF Full Text

Discovery of a potent anti-Zika virus benzamide series targeting the viral protein NS4B.

Saved in:
Bibliographic Details
Title: Discovery of a potent anti-Zika virus benzamide series targeting the viral protein NS4B.
Authors: Chung D; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America., Otsuka Y; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America., Kim E; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America., Ullah S; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America., Kennedy NM; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America., Ngo KH; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Kang J; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America., Tomlinson R; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America., Alejandro B; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America., Barnaby K; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America., Miller J; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America., Shumate J; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America., Teo CF; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Tan YB; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Chew CS; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Kang C; Experimental Drug Development Centre, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Luo D; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.; Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore., Scampavia L; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America., Spicer TP; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America., Bannister TD; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America.
Source: PLoS pathogens [PLoS Pathog] 2026 Apr 03; Vol. 22 (4), pp. e1013609. Date of Electronic Publication: 2026 Apr 03 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41931535
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Discovery of a potent anti-Zika virus benzamide series targeting the viral protein NS4B.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Chung+D%22">Chung D</searchLink>; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America.<br /><searchLink fieldCode="AU" term="%22Otsuka+Y%22">Otsuka Y</searchLink>; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Kim+E%22">Kim E</searchLink>; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America.<br /><searchLink fieldCode="AU" term="%22Ullah+S%22">Ullah S</searchLink>; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Kennedy+NM%22">Kennedy NM</searchLink>; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Ngo+KH%22">Ngo KH</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kang+J%22">Kang J</searchLink>; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America.<br /><searchLink fieldCode="AU" term="%22Tomlinson+R%22">Tomlinson R</searchLink>; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America.<br /><searchLink fieldCode="AU" term="%22Alejandro+B%22">Alejandro B</searchLink>; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America.<br /><searchLink fieldCode="AU" term="%22Barnaby+K%22">Barnaby K</searchLink>; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America.<br /><searchLink fieldCode="AU" term="%22Miller+J%22">Miller J</searchLink>; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America.<br /><searchLink fieldCode="AU" term="%22Shumate+J%22">Shumate J</searchLink>; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Teo+CF%22">Teo CF</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+YB%22">Tan YB</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chew+CS%22">Chew CS</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kang+C%22">Kang C</searchLink>; Experimental Drug Development Centre, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Luo+D%22">Luo D</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.; Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Scampavia+L%22">Scampavia L</searchLink>; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Spicer+TP%22">Spicer TP</searchLink>; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Bannister+TD%22">Bannister TD</searchLink>; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2026 Apr 03; Vol. 22 (4), pp. e1013609. <i>Date of Electronic Publication: </i>2026 Apr 03 (<i>Print Publication: </i>2026).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101238921 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1553-7374 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215537366%22">15537366 </searchLink><i>NLM ISO Abbreviation: </i>PLoS Pathog <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41931535
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1371/journal.ppat.1013609
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e1013609
    Titles:
      – TitleFull: Discovery of a potent anti-Zika virus benzamide series targeting the viral protein NS4B.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Chung D
      – PersonEntity:
          Name:
            NameFull: Otsuka Y
      – PersonEntity:
          Name:
            NameFull: Kim E
      – PersonEntity:
          Name:
            NameFull: Ullah S
      – PersonEntity:
          Name:
            NameFull: Kennedy NM
      – PersonEntity:
          Name:
            NameFull: Ngo KH
      – PersonEntity:
          Name:
            NameFull: Kang J
      – PersonEntity:
          Name:
            NameFull: Tomlinson R
      – PersonEntity:
          Name:
            NameFull: Alejandro B
      – PersonEntity:
          Name:
            NameFull: Barnaby K
      – PersonEntity:
          Name:
            NameFull: Miller J
      – PersonEntity:
          Name:
            NameFull: Shumate J
      – PersonEntity:
          Name:
            NameFull: Teo CF
      – PersonEntity:
          Name:
            NameFull: Tan YB
      – PersonEntity:
          Name:
            NameFull: Chew CS
      – PersonEntity:
          Name:
            NameFull: Kang C
      – PersonEntity:
          Name:
            NameFull: Luo D
      – PersonEntity:
          Name:
            NameFull: Scampavia L
      – PersonEntity:
          Name:
            NameFull: Spicer TP
      – PersonEntity:
          Name:
            NameFull: Bannister TD
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 03
              M: 04
              Text: 2026 Apr 03
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1553-7374
          Numbering:
            – Type: volume
              Value: 22
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: PLoS pathogens
              Type: main
ResultId 1