Downregulation of L-type Ca2+ current in patients with atrial fibrillation results from altered channel gating and disruption of membrane microdomains.
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| Title: | Downregulation of L-type Ca2+ current in patients with atrial fibrillation results from altered channel gating and disruption of membrane microdomains. |
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| Authors: | Balycheva M; National Heart and Lung Institute, Imperial College London, United Kingdom; University of Verona, School of Medicine, Verona, Italy; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin., Reilly-O'Donnell B; National Heart and Lung Institute, Imperial College London, United Kingdom., Alvarez-Laviada A; National Heart and Lung Institute, Imperial College London, United Kingdom., Zhang K; Department of Biomedical Engineering Johns Hopkins University, Baltimore, Maryland., Mazzola M; National Heart and Lung Institute, Imperial College London, United Kingdom; Humanitas Clinical and Research Center, Rozzano, Milan, Italy., Sanchez-Alonso JL; National Heart and Lung Institute, Imperial College London, United Kingdom., Lucarelli C; National Heart and Lung Institute, Imperial College London, United Kingdom; University of Verona, School of Medicine, Verona, Italy., Medvedev RY; National Heart and Lung Institute, Imperial College London, United Kingdom; University of Verona, School of Medicine, Verona, Italy; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin., Molina CE; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany., Schobesberger S; National Heart and Lung Institute, Imperial College London, United Kingdom., Diakonov I; National Heart and Lung Institute, Imperial College London, United Kingdom., Wright PT; National Heart and Lung Institute, Imperial College London, United Kingdom; School of Life and Health Sciences, University of Roehampton, London, United Kingdom., Poulet CE; National Heart and Lung Institute, Imperial College London, United Kingdom., Bork NI; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany., Trayanova NA; Department of Biomedical Engineering Johns Hopkins University, Baltimore, Maryland; Department of Medicine, Alliance for Cardiovascular Diagnostic and Treatment Innovation, Johns Hopkins University, Baltimore, Maryland., Faggian G; University of Verona, School of Medicine, Verona, Italy., Punjabi P; National Heart and Lung Institute, Imperial College London, United Kingdom; Department of Cardiothoracic Surgery, Hammersmith Hospital, National Heart and Lung Institute, Imperial College London, United Kingdom., Nikolaev VO; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany., Glukhov AV; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin. Electronic address: aglukhov@medicine.wisc.edu., Gorelik J; National Heart and Lung Institute, Imperial College London, United Kingdom. Electronic address: j.gorelik@ic.ac.uk. |
| Source: | Heart rhythm [Heart Rhythm] 2026 Jul; Vol. 23 (7), pp. e1170-e1182. Date of Electronic Publication: 2026 Apr 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 101200317 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-3871 (Electronic) Linking ISSN: 15475271 NLM ISO Abbreviation: Heart Rhythm Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41933636 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Downregulation of L-type Ca<superscript>2+</superscript> current in patients with atrial fibrillation results from altered channel gating and disruption of membrane microdomains. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Balycheva+M%22">Balycheva M</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom; University of Verona, School of Medicine, Verona, Italy; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Reilly-O'Donnell+B%22">Reilly-O'Donnell B</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Alvarez-Laviada+A%22">Alvarez-Laviada A</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Zhang+K%22">Zhang K</searchLink>; Department of Biomedical Engineering Johns Hopkins University, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Mazzola+M%22">Mazzola M</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom; Humanitas Clinical and Research Center, Rozzano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sanchez-Alonso+JL%22">Sanchez-Alonso JL</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lucarelli+C%22">Lucarelli C</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom; University of Verona, School of Medicine, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Medvedev+RY%22">Medvedev RY</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom; University of Verona, School of Medicine, Verona, Italy; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Molina+CE%22">Molina CE</searchLink>; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schobesberger+S%22">Schobesberger S</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Diakonov+I%22">Diakonov I</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wright+PT%22">Wright PT</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom; School of Life and Health Sciences, University of Roehampton, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Poulet+CE%22">Poulet CE</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Bork+NI%22">Bork NI</searchLink>; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Trayanova+NA%22">Trayanova NA</searchLink>; Department of Biomedical Engineering Johns Hopkins University, Baltimore, Maryland; Department of Medicine, Alliance for Cardiovascular Diagnostic and Treatment Innovation, Johns Hopkins University, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Faggian+G%22">Faggian G</searchLink>; University of Verona, School of Medicine, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Punjabi+P%22">Punjabi P</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom; Department of Cardiothoracic Surgery, Hammersmith Hospital, National Heart and Lung Institute, Imperial College London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nikolaev+VO%22">Nikolaev VO</searchLink>; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Glukhov+AV%22">Glukhov AV</searchLink>; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin. Electronic address: aglukhov@medicine.wisc.edu.<br /><searchLink fieldCode="AU" term="%22Gorelik+J%22">Gorelik J</searchLink>; National Heart and Lung Institute, Imperial College London, United Kingdom. Electronic address: j.gorelik@ic.ac.uk. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101200317%22">Heart rhythm</searchLink> [Heart Rhythm] 2026 Jul; Vol. 23 (7), pp. e1170-e1182. <i>Date of Electronic Publication: </i>2026 Apr 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101200317 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1556-3871 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215475271%22">15475271 </searchLink><i>NLM ISO Abbreviation: </i>Heart Rhythm <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41933636 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.hrthm.2026.03.1953 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e1170 Titles: – TitleFull: Downregulation of L-type Ca2+ current in patients with atrial fibrillation results from altered channel gating and disruption of membrane microdomains. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Balycheva M – PersonEntity: Name: NameFull: Reilly-O'Donnell B – PersonEntity: Name: NameFull: Alvarez-Laviada A – PersonEntity: Name: NameFull: Zhang K – PersonEntity: Name: NameFull: Mazzola M – PersonEntity: Name: NameFull: Sanchez-Alonso JL – PersonEntity: Name: NameFull: Lucarelli C – PersonEntity: Name: NameFull: Medvedev RY – PersonEntity: Name: NameFull: Molina CE – PersonEntity: Name: NameFull: Schobesberger S – PersonEntity: Name: NameFull: Diakonov I – PersonEntity: Name: NameFull: Wright PT – PersonEntity: Name: NameFull: Poulet CE – PersonEntity: Name: NameFull: Bork NI – PersonEntity: Name: NameFull: Trayanova NA – PersonEntity: Name: NameFull: Faggian G – PersonEntity: Name: NameFull: Punjabi P – PersonEntity: Name: NameFull: Nikolaev VO – PersonEntity: Name: NameFull: Glukhov AV – PersonEntity: Name: NameFull: Gorelik J IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2026 Jul Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1556-3871 Numbering: – Type: volume Value: 23 – Type: issue Value: 7 Titles: – TitleFull: Heart rhythm Type: main |
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