Adult ADHD with comorbid major depression shows a distinguishable polygenic pattern and negative cognitive style.

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Title: Adult ADHD with comorbid major depression shows a distinguishable polygenic pattern and negative cognitive style.
Authors: Kranz TM; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany., McNeill RV; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany., Jacob CP; Department of Psychiatry and Psychotherapy, Medius Hospital of Kirchheim, Kirchheim unter Teck, Germany., Ahrens KF; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany., Neumann RJ; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany., Plichta MM; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany., Kollmann B; Department of Psychiatry and Psychotherapy, Johannes Gutenberg University Medical Center, Mainz, Germany.; Leibniz Institute for Resilience Research, Mainz, Germany., Streit F; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Hector Institute for Artificial Intelligence in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Center for Mental Health (DZPG), partner site Mannheim-Heidelberg-Ulm, Mannheim, Germany., Tüscher O; Department of Psychiatry and Psychotherapy, Johannes Gutenberg University Medical Center, Mainz, Germany.; Leibniz Institute for Resilience Research, Mainz, Germany.; Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, Martin Luther University Halle-Wittenberg (MLU) & German Center for Mental Health (DZPG), partner site Halle-Jena-Magdeburg, Halle, Germany., Lieb K; Department of Psychiatry and Psychotherapy, Johannes Gutenberg University Medical Center, Mainz, Germany., Weber H; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany., Romanos M; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany., Lesch KP; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany.; Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany.; Department of Psychiatry and Neuropsychology, School of Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands., Reif A; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany., Kittel-Schneider S; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany.; Department of Psychiatry and Neurobehavioural Science, University College Cork, Cork, Ireland., Ziegler GC; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany. ziegler_g@ukw.de.; Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany. ziegler_g@ukw.de.
Source: Translational psychiatry [Transl Psychiatry] 2026 Apr 04; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
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  Data: Adult ADHD with comorbid major depression shows a distinguishable polygenic pattern and negative cognitive style.
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  Data: <searchLink fieldCode="AU" term="%22Kranz+TM%22">Kranz TM</searchLink>; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22McNeill+RV%22">McNeill RV</searchLink>; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jacob+CP%22">Jacob CP</searchLink>; Department of Psychiatry and Psychotherapy, Medius Hospital of Kirchheim, Kirchheim unter Teck, Germany.<br /><searchLink fieldCode="AU" term="%22Ahrens+KF%22">Ahrens KF</searchLink>; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Neumann+RJ%22">Neumann RJ</searchLink>; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Plichta+MM%22">Plichta MM</searchLink>; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Kollmann+B%22">Kollmann B</searchLink>; Department of Psychiatry and Psychotherapy, Johannes Gutenberg University Medical Center, Mainz, Germany.; Leibniz Institute for Resilience Research, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Streit+F%22">Streit F</searchLink>; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Hector Institute for Artificial Intelligence in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Center for Mental Health (DZPG), partner site Mannheim-Heidelberg-Ulm, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Tüscher+O%22">Tüscher O</searchLink>; Department of Psychiatry and Psychotherapy, Johannes Gutenberg University Medical Center, Mainz, Germany.; Leibniz Institute for Resilience Research, Mainz, Germany.; Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, Martin Luther University Halle-Wittenberg (MLU) & German Center for Mental Health (DZPG), partner site Halle-Jena-Magdeburg, Halle, Germany.<br /><searchLink fieldCode="AU" term="%22Lieb+K%22">Lieb K</searchLink>; Department of Psychiatry and Psychotherapy, Johannes Gutenberg University Medical Center, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Weber+H%22">Weber H</searchLink>; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Romanos+M%22">Romanos M</searchLink>; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lesch+KP%22">Lesch KP</searchLink>; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany.; Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany.; Department of Psychiatry and Neuropsychology, School of Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Reif+A%22">Reif A</searchLink>; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Kittel-Schneider+S%22">Kittel-Schneider S</searchLink>; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany.; Department of Psychiatry and Neurobehavioural Science, University College Cork, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Ziegler+GC%22">Ziegler GC</searchLink>; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany. ziegler_g@ukw.de.; Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany. ziegler_g@ukw.de.
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  Data: <searchLink fieldCode="JN" term="%22101562664%22">Translational psychiatry</searchLink> [Transl Psychiatry] 2026 Apr 04; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Apr 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101562664 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2158-3188 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221583188%22">21583188 </searchLink><i>NLM ISO Abbreviation: </i>Transl Psychiatry <i>Subsets: </i>MEDLINE
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