An in vivo fitness gene of Toxoplasma, MIC11, is essential for PLP1-mediated egress from host cells.
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| Title: | An in vivo fitness gene of Toxoplasma, MIC11, is essential for PLP1-mediated egress from host cells. |
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| Authors: | Tachibana Y; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan., Gu X; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan., Sasai M; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan.; Department of Immunoparasitology, Center for Infectious Disease Education and Research, The University of Osaka, Osaka, Japan., Kosako H; Division of Cell Signaling, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan., Takashima E; Division of Malaria Research, Proteo-Science Center, Ehime University, Matsuyama, Ehime, Japan., Standley DM; Department of Genome Informatics, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan., Carruthers VB; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA., Soldati-Favre D; Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Yamamoto M; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan. myamamoto@biken.osaka-u.ac.jp.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan. myamamoto@biken.osaka-u.ac.jp.; Department of Immunoparasitology, Center for Infectious Disease Education and Research, The University of Osaka, Osaka, Japan. myamamoto@biken.osaka-u.ac.jp. |
| Source: | Nature communications [Nat Commun] 2026 Apr 04; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-026-71423-x |
