An in vivo fitness gene of Toxoplasma, MIC11, is essential for PLP1-mediated egress from host cells.

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Title: An in vivo fitness gene of Toxoplasma, MIC11, is essential for PLP1-mediated egress from host cells.
Authors: Tachibana Y; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan., Gu X; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan., Sasai M; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan.; Department of Immunoparasitology, Center for Infectious Disease Education and Research, The University of Osaka, Osaka, Japan., Kosako H; Division of Cell Signaling, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan., Takashima E; Division of Malaria Research, Proteo-Science Center, Ehime University, Matsuyama, Ehime, Japan., Standley DM; Department of Genome Informatics, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan., Carruthers VB; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA., Soldati-Favre D; Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Yamamoto M; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan. myamamoto@biken.osaka-u.ac.jp.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan. myamamoto@biken.osaka-u.ac.jp.; Department of Immunoparasitology, Center for Infectious Disease Education and Research, The University of Osaka, Osaka, Japan. myamamoto@biken.osaka-u.ac.jp.
Source: Nature communications [Nat Commun] 2026 Apr 04; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: An in vivo fitness gene of Toxoplasma, MIC11, is essential for PLP1-mediated egress from host cells.
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  Data: <searchLink fieldCode="AU" term="%22Tachibana+Y%22">Tachibana Y</searchLink>; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Gu+X%22">Gu X</searchLink>; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Sasai+M%22">Sasai M</searchLink>; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan.; Department of Immunoparasitology, Center for Infectious Disease Education and Research, The University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kosako+H%22">Kosako H</searchLink>; Division of Cell Signaling, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Takashima+E%22">Takashima E</searchLink>; Division of Malaria Research, Proteo-Science Center, Ehime University, Matsuyama, Ehime, Japan.<br /><searchLink fieldCode="AU" term="%22Standley+DM%22">Standley DM</searchLink>; Department of Genome Informatics, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Carruthers+VB%22">Carruthers VB</searchLink>; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Soldati-Favre+D%22">Soldati-Favre D</searchLink>; Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Yamamoto+M%22">Yamamoto M</searchLink>; Department of Immunoparasitology, Research Institute for Microbial Diseases, The University of Osaka, Osaka, Japan. myamamoto@biken.osaka-u.ac.jp.; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan. myamamoto@biken.osaka-u.ac.jp.; Department of Immunoparasitology, Center for Infectious Disease Education and Research, The University of Osaka, Osaka, Japan. myamamoto@biken.osaka-u.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Apr 04; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Apr 04.
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              Text: 2026 Apr 04
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