Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles.
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| Title: | Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles. |
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| Authors: | Karabova MK; James and Lillian Martin Centre for Stem Cell Research, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Del Ser-Badia A; James and Lillian Martin Centre for Stem Cell Research, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Hedegaard A; James and Lillian Martin Centre for Stem Cell Research, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Washer SJ; James and Lillian Martin Centre for Stem Cell Research, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Baykam Z; James and Lillian Martin Centre for Stem Cell Research, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., O'Brien DP; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Vendrell I; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Hester SS; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Fischer R; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Johnson E; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Melia CE; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Matthews-Palmer TRS; Central Oxford Structural Molecular Imaging Centre, Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; Current affiliation: Division of Structural Biology, The Institute of Cancer Research (ICR), London, UK., Matadeen R; Central Oxford Structural Molecular Imaging Centre, Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK., Santambrogio A; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Metrick MA 2nd; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Vendruscolo M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Keeling S; UK Dementia Research Institute at the University of Cambridge, Cambridge, UK., Cheam KAX; UK Dementia Research Institute at the University of Cambridge, Cambridge, UK., McEwan WA; UK Dementia Research Institute at the University of Cambridge, Cambridge, UK., Kosik KS; Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, California, USA.; Department of Molecular, Cell and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, USA., Day TA; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, USA., James WS; James and Lillian Martin Centre for Stem Cell Research, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Cowley SA; James and Lillian Martin Centre for Stem Cell Research, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. |
| Source: | Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Apr; Vol. 22 (4), pp. e71337. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1552-5279 |
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| DOI: | 10.1002/alz.71337 |
