Unlocking the catalytic mechanism of ultrathin single-atom two-dimensional metal-organic framework nanozymes for dual-mode biosensing of hydrogen peroxide in tumor cells.

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Title: Unlocking the catalytic mechanism of ultrathin single-atom two-dimensional metal-organic framework nanozymes for dual-mode biosensing of hydrogen peroxide in tumor cells.
Authors: Wei YJ; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Tu CQ; School of Pharmacy, Chengdu University, Chengdu 610106, China., Bing YB; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Qin S; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Yang WB; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Liu CX; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Wu WX; School of Pharmacy, Chengdu University, Chengdu 610106, China., Yao K; Guangdong Advanced Carbon Materials Co., Ltd, Zhuhai 519000, China., Chen SX; Guangdong Advanced Carbon Materials Co., Ltd, Zhuhai 519000, China. Electronic address: chenshangxian@kargen.cn., Zhang J; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Liu YH; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China. Electronic address: yanhongliu@scu.edu.cn., Yu XQ; Sichuan Engineering Research Center of Molecular Targeted Diagnostic & Therapeutic Drugs, Department of Chemistry, Xihua University, Chengdu 610039, China; Asymmetric Synthesis and Chiral Technology Key Laboratory of Sichuan Province, Chengdu 610039, China., Wang N; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China. Electronic address: wnchem@scu.edu.cn.
Source: Journal of colloid and interface science [J Colloid Interface Sci] 2026 Sep; Vol. 717, pp. 140416. Date of Electronic Publication: 2026 Apr 04.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0043125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-7103 (Electronic) Linking ISSN: 00219797 NLM ISO Abbreviation: J Colloid Interface Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1095-7103
DOI:10.1016/j.jcis.2026.140416