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Unlocking the catalytic mechanism of ultrathin single-atom two-dimensional metal-organic framework nanozymes for dual-mode biosensing of hydrogen peroxide in tumor cells.

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Title: Unlocking the catalytic mechanism of ultrathin single-atom two-dimensional metal-organic framework nanozymes for dual-mode biosensing of hydrogen peroxide in tumor cells.
Authors: Wei YJ; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Tu CQ; School of Pharmacy, Chengdu University, Chengdu 610106, China., Bing YB; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Qin S; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Yang WB; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Liu CX; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Wu WX; School of Pharmacy, Chengdu University, Chengdu 610106, China., Yao K; Guangdong Advanced Carbon Materials Co., Ltd, Zhuhai 519000, China., Chen SX; Guangdong Advanced Carbon Materials Co., Ltd, Zhuhai 519000, China. Electronic address: chenshangxian@kargen.cn., Zhang J; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China., Liu YH; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China. Electronic address: yanhongliu@scu.edu.cn., Yu XQ; Sichuan Engineering Research Center of Molecular Targeted Diagnostic & Therapeutic Drugs, Department of Chemistry, Xihua University, Chengdu 610039, China; Asymmetric Synthesis and Chiral Technology Key Laboratory of Sichuan Province, Chengdu 610039, China., Wang N; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China. Electronic address: wnchem@scu.edu.cn.
Source: Journal of colloid and interface science [J Colloid Interface Sci] 2026 Sep; Vol. 717, pp. 140416. Date of Electronic Publication: 2026 Apr 04.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0043125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-7103 (Electronic) Linking ISSN: 00219797 NLM ISO Abbreviation: J Colloid Interface Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Unlocking the catalytic mechanism of ultrathin single-atom two-dimensional metal-organic framework nanozymes for dual-mode biosensing of hydrogen peroxide in tumor cells.
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  Data: <searchLink fieldCode="AU" term="%22Wei+YJ%22">Wei YJ</searchLink>; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China.<br /><searchLink fieldCode="AU" term="%22Tu+CQ%22">Tu CQ</searchLink>; School of Pharmacy, Chengdu University, Chengdu 610106, China.<br /><searchLink fieldCode="AU" term="%22Bing+YB%22">Bing YB</searchLink>; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China.<br /><searchLink fieldCode="AU" term="%22Qin+S%22">Qin S</searchLink>; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China.<br /><searchLink fieldCode="AU" term="%22Yang+WB%22">Yang WB</searchLink>; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China.<br /><searchLink fieldCode="AU" term="%22Liu+CX%22">Liu CX</searchLink>; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China.<br /><searchLink fieldCode="AU" term="%22Wu+WX%22">Wu WX</searchLink>; School of Pharmacy, Chengdu University, Chengdu 610106, China.<br /><searchLink fieldCode="AU" term="%22Yao+K%22">Yao K</searchLink>; Guangdong Advanced Carbon Materials Co., Ltd, Zhuhai 519000, China.<br /><searchLink fieldCode="AU" term="%22Chen+SX%22">Chen SX</searchLink>; Guangdong Advanced Carbon Materials Co., Ltd, Zhuhai 519000, China. Electronic address: chenshangxian@kargen.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China.<br /><searchLink fieldCode="AU" term="%22Liu+YH%22">Liu YH</searchLink>; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China. Electronic address: yanhongliu@scu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yu+XQ%22">Yu XQ</searchLink>; Sichuan Engineering Research Center of Molecular Targeted Diagnostic & Therapeutic Drugs, Department of Chemistry, Xihua University, Chengdu 610039, China; Asymmetric Synthesis and Chiral Technology Key Laboratory of Sichuan Province, Chengdu 610039, China.<br /><searchLink fieldCode="AU" term="%22Wang+N%22">Wang N</searchLink>; Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China. Electronic address: wnchem@scu.edu.cn.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0043125 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-7103 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219797%22">00219797 </searchLink><i>NLM ISO Abbreviation: </i>J Colloid Interface Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jcis.2026.140416
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              M: 09
              Text: 2026 Sep
              Type: published
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