Integration of network toxicology and transcriptomics reveals the potential regulatory role of the 'Arecoline/4-NQO-AKT1-m6A factor' axis in the development of OSCC.

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Title: Integration of network toxicology and transcriptomics reveals the potential regulatory role of the 'Arecoline/4-NQO-AKT1-m6A factor' axis in the development of OSCC.
Authors: Qiu Y; Department of Stomatology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China., Wang Y; Department of Stomatology, Qinhuangdao Haigang Hospital, Qinhuangdao, Hebei, China., Zhao J; Department of Stomatology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China., Cheng Y; Department of Dermotology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China., Liu Y; Department of Stomatology, The Second Hospital of Shijiazhuang, Shijiazhuang, Hebei, China., Xu H; Department of Stomatology, The Second Hospital of Shijiazhuang, Shijiazhuang, Hebei, China., Zhuang Z; Department of Stomatology, Affiliated Hospital of Hebei University, Baoding, Hebei, China., Lv F; Department of Stomatology, Affiliated Hospital of Hebei University, Baoding, Hebei, China.
Source: Frontiers in oncology [Front Oncol] 2026 Mar 23; Vol. 16, pp. 1739418. Date of Electronic Publication: 2026 Mar 23 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2234-943X
DOI:10.3389/fonc.2026.1739418