Targeting leukemic stem and progenitor cells expressing different BCR::ABL1 levels: antileukemic activity of asciminib with or without TKIs.
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| Title: | Targeting leukemic stem and progenitor cells expressing different BCR::ABL1 levels: antileukemic activity of asciminib with or without TKIs. |
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| Authors: | Massimino M; Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico - S. Marco', Catania, Italy., Tirrò E; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico - S. Marco', Catania, Italy., Romano C; Department of Medical and Surgical Sciences and Advanced Technologies 'G.F. Ingrassia,' Anatomic Pathology, University of Catania, Catania, Italy., Stella S; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico - S. Marco', Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy., Tomarchio C; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico - S. Marco', Catania, Italy.; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Vitale SR; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico - S. Marco', Catania, Italy., Manzella L; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico - S. Marco', Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy., Di Raimondo F; Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy.; Division of Hematology, A.O.U. Policlinico 'G. Rodolico - S. Marco', Catania, Italy., Stagno F; Hematology Section, A.O.U. Policlinico 'G. Martino', University of Messina, Messina, Italy., Vigneri P; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico - S. Marco', Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.; Division of Oncology, Humanitas Istituto Clinico Catanese, Catania, Italy. |
| Source: | Frontiers in pharmacology [Front Pharmacol] 2026 Mar 23; Vol. 17, pp. 1780054. Date of Electronic Publication: 2026 Mar 23 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1663-9812 |
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| DOI: | 10.3389/fphar.2026.1780054 |
