Prevention of oral mucositis in patients undergoing cancer chemotherapy using betamethasone mouthwash: A multicenter randomized controlled trial protocol.
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| Title: | Prevention of oral mucositis in patients undergoing cancer chemotherapy using betamethasone mouthwash: A multicenter randomized controlled trial protocol. |
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| Authors: | Soutome S; Department of Oral Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Center for Clinical and Translational Research, Toyama University Hospital, Toyama, Japan., Hamada T; Department of Oral and Maxillofacial Surgery, Social Medical Corporation Hakuaikai Sagara Hospital, Kagoshima, Japan., Nishi H; Department of General Dentistry, Hiroshima University Hospital, Hiroshima, Japan., Iwata E; Department of Oral and Maxillofacial Surgery, Kakogawa Central City Hospital, Hyogo, Japan., Nakahara H; Department of Dentistry and Oral Surgery, Osaka Metropolitan University Hospital, Osaka, Japan., Yamamoto T; Department of Dental Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan., Matsumura T; Department of Oral and Maxillofacial Surgery, Wakayama Medical University, Wakayama, Japan., Nishikawa M; Department of Dentistry and Oral Surgery, Nishichita General Hospital, Aichi, Japan., Tomihara K; Division of Oral and Maxillofacial Surgery, Niigata University Graduate School of Medical and Dental Science, Niigata, Japan., Ueki K; Department of Oral and Maxillofacial Surgery, Division of Medicine, Interdisciplinary Graduate School, University of Yamanashi, Yamanashi, Japan., Noda M; Department of Endodontics, School of Dentistry, Faculties and Graduate Schools, Iwate Medical University, Iwate, Japan., Shimanishi M; Department of Dental and Oral Surgery, Oji General Hospital, Hokkaido, Japan., Funahara M; School of Oral Health Sciences Faculty of Dentistry, Kyushu Dental University, Fukuoka, Japan., Kawahara M; Laboratory of Clinical Pharmacy, School of Pharmacy, Aichi Gakuin University, Aichi, Japan., Yamamura Y; Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Juntendo University, Tokyo, Japan., Matsuda S; Department of Dentistry and Oral Surgery, Unit of Sensory and Locomotor Medicine, Division of Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan., Yoshida K; Department of Drug Safety and Risk Management, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan., Kanazawa S; Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Otsuji M; Dentistry/Oral and Maxillofacial Surgery, Kagoshima City Hospital, Kagoshima, Japan., Natsume N; Division of Research and Treatment for Oral Maxillofacial Congenital Anomalies, School of Dentistry, Aichi Gakuin University, Aichi, Japan., Umeda M; Division of Research and Treatment for Oral Maxillofacial Congenital Anomalies, School of Dentistry, Aichi Gakuin University, Aichi, Japan. |
| Corporate Authors: | Research Committee of the Japanese Society of Oral Care |
| Source: | PloS one [PLoS One] 2026 Apr 08; Vol. 21 (4), pp. e0345991. Date of Electronic Publication: 2026 Apr 08 (Print Publication: 2026). |
| Publication Type: | Journal Article; Multicenter Study; Randomized Controlled Trial; Clinical Trial, Phase II |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41950207 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Prevention of oral mucositis in patients undergoing cancer chemotherapy using betamethasone mouthwash: A multicenter randomized controlled trial protocol. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Soutome+S%22">Soutome S</searchLink>; Department of Oral Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Center for Clinical and Translational Research, Toyama University Hospital, Toyama, Japan.<br /><searchLink fieldCode="AU" term="%22Hamada+T%22">Hamada T</searchLink>; Department of Oral and Maxillofacial Surgery, Social Medical Corporation Hakuaikai Sagara Hospital, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Nishi+H%22">Nishi H</searchLink>; Department of General Dentistry, Hiroshima University Hospital, Hiroshima, Japan.<br /><searchLink fieldCode="AU" term="%22Iwata+E%22">Iwata E</searchLink>; Department of Oral and Maxillofacial Surgery, Kakogawa Central City Hospital, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Nakahara+H%22">Nakahara H</searchLink>; Department of Dentistry and Oral Surgery, Osaka Metropolitan University Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+T%22">Yamamoto T</searchLink>; Department of Dental Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Matsumura+T%22">Matsumura T</searchLink>; Department of Oral and Maxillofacial Surgery, Wakayama Medical University, Wakayama, Japan.<br /><searchLink fieldCode="AU" term="%22Nishikawa+M%22">Nishikawa M</searchLink>; Department of Dentistry and Oral Surgery, Nishichita General Hospital, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Tomihara+K%22">Tomihara K</searchLink>; Division of Oral and Maxillofacial Surgery, Niigata University Graduate School of Medical and Dental Science, Niigata, Japan.<br /><searchLink fieldCode="AU" term="%22Ueki+K%22">Ueki K</searchLink>; Department of Oral and Maxillofacial Surgery, Division of Medicine, Interdisciplinary Graduate School, University of Yamanashi, Yamanashi, Japan.<br /><searchLink fieldCode="AU" term="%22Noda+M%22">Noda M</searchLink>; Department of Endodontics, School of Dentistry, Faculties and Graduate Schools, Iwate Medical University, Iwate, Japan.<br /><searchLink fieldCode="AU" term="%22Shimanishi+M%22">Shimanishi M</searchLink>; Department of Dental and Oral Surgery, Oji General Hospital, Hokkaido, Japan.<br /><searchLink fieldCode="AU" term="%22Funahara+M%22">Funahara M</searchLink>; School of Oral Health Sciences Faculty of Dentistry, Kyushu Dental University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Kawahara+M%22">Kawahara M</searchLink>; Laboratory of Clinical Pharmacy, School of Pharmacy, Aichi Gakuin University, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamura+Y%22">Yamamura Y</searchLink>; Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Juntendo University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Matsuda+S%22">Matsuda S</searchLink>; Department of Dentistry and Oral Surgery, Unit of Sensory and Locomotor Medicine, Division of Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshida+K%22">Yoshida K</searchLink>; Department of Drug Safety and Risk Management, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kanazawa+S%22">Kanazawa S</searchLink>; Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Otsuji+M%22">Otsuji M</searchLink>; Dentistry/Oral and Maxillofacial Surgery, Kagoshima City Hospital, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Natsume+N%22">Natsume N</searchLink>; Division of Research and Treatment for Oral Maxillofacial Congenital Anomalies, School of Dentistry, Aichi Gakuin University, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Umeda+M%22">Umeda M</searchLink>; Division of Research and Treatment for Oral Maxillofacial Congenital Anomalies, School of Dentistry, Aichi Gakuin University, Aichi, Japan. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Research+Committee+of+the+Japanese+Society+of+Oral+Care%22">Research Committee of the Japanese Society of Oral Care</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2026 Apr 08; Vol. 21 (4), pp. e0345991. <i>Date of Electronic Publication: </i>2026 Apr 08 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study; Randomized Controlled Trial; Clinical Trial, Phase II – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101285081 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-6203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219326203%22">19326203 </searchLink><i>NLM ISO Abbreviation: </i>PLoS One <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41950207 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1371/journal.pone.0345991 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e0345991 Titles: – TitleFull: Prevention of oral mucositis in patients undergoing cancer chemotherapy using betamethasone mouthwash: A multicenter randomized controlled trial protocol. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Soutome S – PersonEntity: Name: NameFull: Hamada T – PersonEntity: Name: NameFull: Nishi H – PersonEntity: Name: NameFull: Iwata E – PersonEntity: Name: NameFull: Nakahara H – PersonEntity: Name: NameFull: Yamamoto T – PersonEntity: Name: NameFull: Matsumura T – PersonEntity: Name: NameFull: Nishikawa M – PersonEntity: Name: NameFull: Tomihara K – PersonEntity: Name: NameFull: Ueki K – PersonEntity: Name: NameFull: Noda M – PersonEntity: Name: NameFull: Shimanishi M – PersonEntity: Name: NameFull: Funahara M – PersonEntity: Name: NameFull: Kawahara M – PersonEntity: Name: NameFull: Yamamura Y – PersonEntity: Name: NameFull: Matsuda S – PersonEntity: Name: NameFull: Yoshida K – PersonEntity: Name: NameFull: Kanazawa S – PersonEntity: Name: NameFull: Otsuji M – PersonEntity: Name: NameFull: Natsume N – PersonEntity: Name: NameFull: Umeda M IsPartOfRelationships: – BibEntity: Dates: – D: 08 M: 04 Text: 2026 Apr 08 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1932-6203 Numbering: – Type: volume Value: 21 – Type: issue Value: 4 Titles: – TitleFull: PloS one Type: main |
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