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Allosteric activation of pyruvate carboxylase by Dracoflavan B2 enhances endothelial energy metabolism to attenuate myocardial infarction.

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Title: Allosteric activation of pyruvate carboxylase by Dracoflavan B2 enhances endothelial energy metabolism to attenuate myocardial infarction.
Authors: Hong C; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China; Modern Research Center for Traditional Chinese Medicine, Beijing Institute of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China., Li H; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China; Modern Research Center for Traditional Chinese Medicine, Beijing Institute of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China., Liu RY; School of Bioengineering, Tianjin University of Science and Technology, Tianjin 300457, China., Wang R; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China; Modern Research Center for Traditional Chinese Medicine, Beijing Institute of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China., Sun YJ; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China; Modern Research Center for Traditional Chinese Medicine, Beijing Institute of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China., Huang YL; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China; Modern Research Center for Traditional Chinese Medicine, Beijing Institute of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China., Wei TT; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100080, China., Tu PF; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100080, China. Electronic address: pengfeitu@bjmu.edu.cn., Zeng KW; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100080, China; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing 100080, China. Electronic address: ZKW@bjmu.edu.cn., Li J; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China; Modern Research Center for Traditional Chinese Medicine, Beijing Institute of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China. Electronic address: drlj666@163.com.
Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2026 Jun; Vol. 155, pp. 158145. Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article
Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1618-095X
DOI:10.1016/j.phymed.2026.158145