Identification of an intrusive-hypervigilant phenotype of posttraumatic stress symptoms with unique stress peptide and amygdala functional connectivity profiles.

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Title: Identification of an intrusive-hypervigilant phenotype of posttraumatic stress symptoms with unique stress peptide and amygdala functional connectivity profiles.
Authors: Clancy KJ; Division of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA. kclancy@mclean.harvard.edu.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA. kclancy@mclean.harvard.edu., Ravichandran C; Division of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Jobson SA; Division of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., May V; Larner College of Medicine, University of Vermont, Burlington, VT, USA., Hammack SE; Department of Psychology, University of Vermont, Burlington, VT, USA., Carlezon WA Jr; Division of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Ressler KJ; Division of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Rauch SL; Division of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Rosso IM; Division of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA. irosso@mgb.org.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA. irosso@mgb.org.
Source: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2026 Apr 08. Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1740-634X
DOI:10.1038/s41386-026-02396-0