Trajectories of plasma and CSF MTBR-tau243 and phosphorylated-tau species across the Alzheimer's disease continuum.

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Title: Trajectories of plasma and CSF MTBR-tau243 and phosphorylated-tau species across the Alzheimer's disease continuum.
Authors: Collij LE; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden. lyduine.collij@med.lu.se.; Radiology and Nuclear Medicine, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands. lyduine.collij@med.lu.se.; Brain Imaging, Amsterdam Neuroscience, Amsterdam, The Netherlands. lyduine.collij@med.lu.se., Salvadó G; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden., Horie K; Tracy Family Stable Isotope Labeling Quantitation (SILQ) Center, Washington University School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Eisai, Inc., Nutley, NJ, USA., Barthélemy NR; Tracy Family Stable Isotope Labeling Quantitation (SILQ) Center, Washington University School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Betthauser TJ; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Strandberg O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden., Smith R; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Palmqvist S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Schindler SE; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA., Ossenkoppele R; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Neurology, Alzheimercenter Amsterdam, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.; Neurodegeneration, Amsterdam Neuroscience, Amsterdam, The Netherlands., Janelidze S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden., Mattsson-Carlgren N; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden., Bateman RJ; Tracy Family Stable Isotope Labeling Quantitation (SILQ) Center, Washington University School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden. oskar.hansson@med.lu.se.
Source: Nature communications [Nat Commun] 2026 Apr 09; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-026-71732-1