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Shifts in protein aggregate stability define proteostasis decline in the aging human brain.

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Title: Shifts in protein aggregate stability define proteostasis decline in the aging human brain.
Authors: Anderton E; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.; USC Leonard Davis School of Gerontology, University of Southern California, 3715 McClintock Ave, Los Angeles, CA, 90191, USA., Burton JB; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA., King CD; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA., Foulger AC; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA., Bhaumik D; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA., Timonina D; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA., Mayeri Z; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA., Chamoli M; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA., Andersen JK; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA., Schilling B; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA., Lithgow GJ; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 18. Date of Electronic Publication: 2026 Apr 18.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Shifts in protein aggregate stability define proteostasis decline in the aging human brain.
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  Data: <searchLink fieldCode="AU" term="%22Anderton+E%22">Anderton E</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.; USC Leonard Davis School of Gerontology, University of Southern California, 3715 McClintock Ave, Los Angeles, CA, 90191, USA.<br /><searchLink fieldCode="AU" term="%22Burton+JB%22">Burton JB</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22King+CD%22">King CD</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22Foulger+AC%22">Foulger AC</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22Bhaumik+D%22">Bhaumik D</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22Timonina+D%22">Timonina D</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22Mayeri+Z%22">Mayeri Z</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22Chamoli+M%22">Chamoli M</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22Andersen+JK%22">Andersen JK</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22Schilling+B%22">Schilling B</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.<br /><searchLink fieldCode="AU" term="%22Lithgow+GJ%22">Lithgow GJ</searchLink>; Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Apr 18. <i>Date of Electronic Publication: </i>2026 Apr 18.
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              Text: 2026 Apr 18
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