Rapid CAR screening and circRNA-driven CAR-NK cells for persistent shed-resistant immunotherapy.
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| Title: | Rapid CAR screening and circRNA-driven CAR-NK cells for persistent shed-resistant immunotherapy. |
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| Authors: | Chung JY; Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.; KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul, 02447, Republic of Korea., Hong J; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea., Yee SM; Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea., Lim HW; Cancer Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea., Lee D; Department of Pharmacology, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea., Yoon S; Corporate Research & Development Center, UCI Therapeutics, Seoul, 04784, Republic of Korea., Lee SH; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, K1N 6N5, Canada.; Ottawa Institute of Systems Biology, Faculty of Medicine and Centre for Infection, Immunity, and Inflammation, Faculty of Medicine, University of Ottawa, Ontario, K1N 6N5, Canada., Jung Y; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea., Shin SH; Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea., Kim SC; Division of Hepato-Biliary and Pancreatic Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, 05505, Seoul, Republic of Korea., Lee CH; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. chlee-antibody@snu.ac.kr.; Cancer Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. chlee-antibody@snu.ac.kr.; Department of Pharmacology, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. chlee-antibody@snu.ac.kr.; BK21 FOUR Biomedical Science Project, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. chlee-antibody@snu.ac.kr.; Wide River Institute of Immunology, Seoul National University, Hongcheon, 25159, Republic of Korea. chlee-antibody@snu.ac.kr., Jang M; Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea. mihue@kist.re.kr.; KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul, 02447, Republic of Korea. mihue@kist.re.kr.; Division of Bio-Medical Science and Technology, KIST School, University of Science and Technology (UST), Seoul, 02792, Republic of Korea. mihue@kist.re.kr. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Apr 10; Vol. 11 (1). Date of Electronic Publication: 2026 Apr 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2059-3635 |
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| DOI: | 10.1038/s41392-026-02623-6 |
