Systemic curcumin administration mitigates neuropathic pain in a rat model of trigeminal neuralgia by suppressing TNF-α and pSTAT3 signaling.

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Title: Systemic curcumin administration mitigates neuropathic pain in a rat model of trigeminal neuralgia by suppressing TNF-α and pSTAT3 signaling.
Authors: Arini DS; Department of Oral Health Science and Social Welfare, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Perdana LP; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Fabillar J Jr; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Miyagi M; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Ikutame D; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Koike K; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Suma S; Department of Preventive Dentistry, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Ichinomiya M; Department of Oral Health Science and Social Welfare, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Matsuka Y; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Kataoka K; Department of Oral Health Science and Social Welfare, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.; Department of Preventive Dentistry, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.
Source: Molecular pain [Mol Pain] 2026 Jan-Dec; Vol. 22, pp. 17448069261445281. Date of Electronic Publication: 2026 Apr 11.
Publication Type: Journal Article
Journal Info: Publisher: Sage Publications Inc Country of Publication: United States NLM ID: 101242662 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8069 (Electronic) Linking ISSN: 17448069 NLM ISO Abbreviation: Mol Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1744-8069
DOI:10.1177/17448069261445281