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Systemic curcumin administration mitigates neuropathic pain in a rat model of trigeminal neuralgia by suppressing TNF-α and pSTAT3 signaling.

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Title: Systemic curcumin administration mitigates neuropathic pain in a rat model of trigeminal neuralgia by suppressing TNF-α and pSTAT3 signaling.
Authors: Arini DS; Department of Oral Health Science and Social Welfare, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Perdana LP; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Fabillar J Jr; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Miyagi M; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Ikutame D; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Koike K; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Suma S; Department of Preventive Dentistry, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Ichinomiya M; Department of Oral Health Science and Social Welfare, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Matsuka Y; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan., Kataoka K; Department of Oral Health Science and Social Welfare, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.; Department of Preventive Dentistry, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.
Source: Molecular pain [Mol Pain] 2026 Jan-Dec; Vol. 22, pp. 17448069261445281. Date of Electronic Publication: 2026 Apr 11.
Publication Type: Journal Article
Journal Info: Publisher: Sage Publications Inc Country of Publication: United States NLM ID: 101242662 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8069 (Electronic) Linking ISSN: 17448069 NLM ISO Abbreviation: Mol Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Systemic curcumin administration mitigates neuropathic pain in a rat model of trigeminal neuralgia by suppressing TNF-α and pSTAT3 signaling.
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  Data: <searchLink fieldCode="AU" term="%22Arini+DS%22">Arini DS</searchLink>; Department of Oral Health Science and Social Welfare, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Perdana+LP%22">Perdana LP</searchLink>; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Fabillar+J+Jr%22">Fabillar J Jr</searchLink>; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Miyagi+M%22">Miyagi M</searchLink>; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Ikutame+D%22">Ikutame D</searchLink>; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Koike+K%22">Koike K</searchLink>; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Suma+S%22">Suma S</searchLink>; Department of Preventive Dentistry, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Ichinomiya+M%22">Ichinomiya M</searchLink>; Department of Oral Health Science and Social Welfare, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Matsuka+Y%22">Matsuka Y</searchLink>; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Kataoka+K%22">Kataoka K</searchLink>; Department of Oral Health Science and Social Welfare, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.; Department of Preventive Dentistry, Graduate School of Biomedical Science, Tokushima University, Tokushima, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101242662%22">Molecular pain</searchLink> [Mol Pain] 2026 Jan-Dec; Vol. 22, pp. 17448069261445281. <i>Date of Electronic Publication: </i>2026 Apr 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Sage+Publications+Inc%22">Sage Publications Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101242662 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1744-8069 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217448069%22">17448069 </searchLink><i>NLM ISO Abbreviation: </i>Mol Pain <i>Subsets: </i>MEDLINE
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        Value: 10.1177/17448069261445281
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              Text: 2026 Jan-Dec
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