Ethyl acetate extract of Lactococcus lactis KR-050L suppresses IL-6/STAT3 signaling in Hep3B cells and alleviates DSS-induced colitis in mice.

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Title: Ethyl acetate extract of Lactococcus lactis KR-050L suppresses IL-6/STAT3 signaling in Hep3B cells and alleviates DSS-induced colitis in mice.
Authors: Bak SG; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea., Chandimali N; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea; Department of Applied Biotechnology, University of Science and Technology (UST), Daejeon 34113, Korea., Bae J; Functional Food Research Institute, Industry-university Cooperation Foundation, Daegu-hanny University, Gyeongsan 38610, Korea., Lee DS; Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 61452, Korea., Lee SW; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea., Park EJ; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea., Lim HJ; Scripps Korea Antibody Institute, Chuncheon 24341, Korea., Won YS; Division of Bioresource Integration Research, Honam National Institute of Biological Resources, Mokpo 58762, Korea., Rho MC; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea. Electronic address: rho-m@kribb.re.kr., Lee SJ; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea; Department of Applied Biotechnology, University of Science and Technology (UST), Daejeon 34113, Korea. Electronic address: seung99@kribb.re.kr.
Source: Journal of biotechnology [J Biotechnol] 2026 Jul; Vol. 415, pp. 145-151. Date of Electronic Publication: 2026 Apr 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8411927 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4863 (Electronic) Linking ISSN: 01681656 NLM ISO Abbreviation: J Biotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ethyl acetate extract of Lactococcus lactis KR-050L suppresses IL-6/STAT3 signaling in Hep3B cells and alleviates DSS-induced colitis in mice.
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  Data: <searchLink fieldCode="AU" term="%22Bak+SG%22">Bak SG</searchLink>; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea.<br /><searchLink fieldCode="AU" term="%22Chandimali+N%22">Chandimali N</searchLink>; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea; Department of Applied Biotechnology, University of Science and Technology (UST), Daejeon 34113, Korea.<br /><searchLink fieldCode="AU" term="%22Bae+J%22">Bae J</searchLink>; Functional Food Research Institute, Industry-university Cooperation Foundation, Daegu-hanny University, Gyeongsan 38610, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+DS%22">Lee DS</searchLink>; Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 61452, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SW%22">Lee SW</searchLink>; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea.<br /><searchLink fieldCode="AU" term="%22Park+EJ%22">Park EJ</searchLink>; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea.<br /><searchLink fieldCode="AU" term="%22Lim+HJ%22">Lim HJ</searchLink>; Scripps Korea Antibody Institute, Chuncheon 24341, Korea.<br /><searchLink fieldCode="AU" term="%22Won+YS%22">Won YS</searchLink>; Division of Bioresource Integration Research, Honam National Institute of Biological Resources, Mokpo 58762, Korea.<br /><searchLink fieldCode="AU" term="%22Rho+MC%22">Rho MC</searchLink>; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea. Electronic address: rho-m@kribb.re.kr.<br /><searchLink fieldCode="AU" term="%22Lee+SJ%22">Lee SJ</searchLink>; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea; Department of Applied Biotechnology, University of Science and Technology (UST), Daejeon 34113, Korea. Electronic address: seung99@kribb.re.kr.
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  Data: <searchLink fieldCode="JN" term="%228411927%22">Journal of biotechnology</searchLink> [J Biotechnol] 2026 Jul; Vol. 415, pp. 145-151. <i>Date of Electronic Publication: </i>2026 Apr 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Publishers%22">Elsevier Science Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8411927 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4863 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201681656%22">01681656 </searchLink><i>NLM ISO Abbreviation: </i>J Biotechnol <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.jbiotec.2026.04.006
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      – Code: eng
        Text: English
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        StartPage: 145
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      – TitleFull: Ethyl acetate extract of Lactococcus lactis KR-050L suppresses IL-6/STAT3 signaling in Hep3B cells and alleviates DSS-induced colitis in mice.
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              Text: 2026 Jul
              Type: published
              Y: 2026
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