Mutagenic and carcinogenic potency determinations for NDMA support the cumulative dose assumption underpinning the less-than-lifetime Threshold of Toxicological Concern.
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| Title: | Mutagenic and carcinogenic potency determinations for NDMA support the cumulative dose assumption underpinning the less-than-lifetime Threshold of Toxicological Concern. |
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| Authors: | Wills JW; Non-Clinical Safety, GSK R&D Stevenage, Stevenage, UK. john.w.wills@gsk.com., White A; Non-Clinical Safety, GSK R&D Stevenage, Stevenage, UK., Harte DSG; Occupational and Product Quality Toxicology, GSC Engineering and Global EHS, Stevenage, UK., Buckley R; Non-Clinical Safety, GSK R&D Stevenage, Stevenage, UK., Harvey JS; Non-Clinical Safety, GSK R&D Stevenage, Stevenage, UK., Lynch AM; Non-Clinical Safety, GSK R&D Stevenage, Stevenage, UK. anthony.m.lynch@gsk.com. |
| Source: | Archives of toxicology [Arch Toxicol] 2026 Apr 14. Date of Electronic Publication: 2026 Apr 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1432-0738 |
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| DOI: | 10.1007/s00204-026-04385-0 |
