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Engineering a robust IsPETase for energy-efficient PET depolymerization in natural seawater at ambient temperatures.

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Title: Engineering a robust IsPETase for energy-efficient PET depolymerization in natural seawater at ambient temperatures.
Authors: Huang X; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China., Jia Q; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China., Li G; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China., Yang X; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China., Xu S; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China., Liu J; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China., Li W; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China., Liu Y; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China., Xie W; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China. xiewei6@mail.sysu.edu.cn., Cao L; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China. caolch5@mail.sysu.edu.cn.
Source: Advanced biotechnology [Adv Biotechnol (Singap)] 2026 Apr 15; Vol. 4 (2). Date of Electronic Publication: 2026 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Singapore Country of Publication: Singapore NLM ID: 9918821788106676 Publication Model: Electronic Cited Medium: Internet ISSN: 2948-2801 (Electronic) Linking ISSN: 29482801 NLM ISO Abbreviation: Adv Biotechnol (Singap) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Engineering a robust IsPETase for energy-efficient PET depolymerization in natural seawater at ambient temperatures.
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  Data: <searchLink fieldCode="AU" term="%22Huang+X%22">Huang X</searchLink>; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China.<br /><searchLink fieldCode="AU" term="%22Jia+Q%22">Jia Q</searchLink>; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China.<br /><searchLink fieldCode="AU" term="%22Li+G%22">Li G</searchLink>; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China.<br /><searchLink fieldCode="AU" term="%22Xu+S%22">Xu S</searchLink>; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China.<br /><searchLink fieldCode="AU" term="%22Xie+W%22">Xie W</searchLink>; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China. xiewei6@mail.sysu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Cao+L%22">Cao L</searchLink>; State Key Laboratory of Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangzhou Innovation Center of Biotechnology and Biomanufacturing, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China. caolch5@mail.sysu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229918821788106676%22">Advanced biotechnology</searchLink> [Adv Biotechnol (Singap)] 2026 Apr 15; Vol. 4 (2). <i>Date of Electronic Publication: </i>2026 Apr 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature+Singapore%22">Springer Nature Singapore </searchLink><i>Country of Publication: </i>Singapore <i>NLM ID: </i>9918821788106676 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2948-2801 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2229482801%22">29482801 </searchLink><i>NLM ISO Abbreviation: </i>Adv Biotechnol (Singap) <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1007/s44307-026-00104-z
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              Text: 2026 Apr 15
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