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Patient-derived pediatric brain tumor orthotopic xenografts and tumor organoids faithfully recapitulate primary tumors.

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Bibliographic Details
Title: Patient-derived pediatric brain tumor orthotopic xenografts and tumor organoids faithfully recapitulate primary tumors.
Authors: Williams JS; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Farmer DM; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Li Q; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Friske JD; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Grenet J; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Robinson S; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Mercer KS; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Goel V; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Janke L; Comparative Pathology Core, St. Jude Children's Research Hospital, Memphis, TN, USA., He L; Department of Host Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA., Klimo P; Department of Surgery, Le Bonheur Children's Hospital, Memphis, TN, USA., Chiang JC; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Robinson GW; Department of Neuro-Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Orr BA; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Roussel MF; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Source: Science advances [Sci Adv] 2026 Apr 17; Vol. 12 (16), pp. eaea4966. Date of Electronic Publication: 2026 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2375-2548
DOI:10.1126/sciadv.aea4966