Dysregulated nuclear Lamin B1 in DYT1 dystonia thickens nuclear lamina and disrupts 14-3-3 proteins.

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Title: Dysregulated nuclear Lamin B1 in DYT1 dystonia thickens nuclear lamina and disrupts 14-3-3 proteins.
Authors: Duan Y; Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, USA., Sepehrimanesh M; Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, USA., Hosain MA; Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, USA., Cui H; Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, USA., Stagray J; Department of Biology, University of Louisiana at Lafayette, Lafayette, LA, USA., Shen X; Department of Pathology and Translational Pathobiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, USA., Xiao Y; Shared Instrumentation Facility, Louisiana State University, Baton Rouge, LA, USA., Li Y; Department of Neurology, Norman Fixel Institute for Neurological Diseases, College of Medicine, University of Florida, Gainesville, FL, USA., Zhang CL; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Ding B; Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, USA. Baojin.ding@lsuhs.edu.
Source: Cell death discovery [Cell Death Discov] 2026 Apr 15; Vol. 12 (1). Date of Electronic Publication: 2026 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2058-7716
DOI:10.1038/s41420-026-03090-2