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Dopamine D2-receptor blockade in humans disrupts the effect of effort on learning.

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Title: Dopamine D2-receptor blockade in humans disrupts the effect of effort on learning.
Authors: Jarvis H; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia., Obawede O; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia., Huynh AQ; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia., Coxon JP; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia., Bellgrove MA; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia., Chong TT; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia.; Department of Neurology, Alfred Health, Melbourne, Australia.; Department of Clinical Neurosciences, St Vincent's Hospital, Melbourne, Australia.
Source: PLoS biology [PLoS Biol] 2026 Apr 16; Vol. 24 (4), pp. e3003765. Date of Electronic Publication: 2026 Apr 16 (Print Publication: 2026).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dopamine D2-receptor blockade in humans disrupts the effect of effort on learning.
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  Data: <searchLink fieldCode="AU" term="%22Jarvis+H%22">Jarvis H</searchLink>; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia.<br /><searchLink fieldCode="AU" term="%22Obawede+O%22">Obawede O</searchLink>; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia.<br /><searchLink fieldCode="AU" term="%22Huynh+AQ%22">Huynh AQ</searchLink>; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia.<br /><searchLink fieldCode="AU" term="%22Coxon+JP%22">Coxon JP</searchLink>; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia.<br /><searchLink fieldCode="AU" term="%22Bellgrove+MA%22">Bellgrove MA</searchLink>; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia.<br /><searchLink fieldCode="AU" term="%22Chong+TT%22">Chong TT</searchLink>; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia.; Department of Neurology, Alfred Health, Melbourne, Australia.; Department of Clinical Neurosciences, St Vincent's Hospital, Melbourne, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101183755%22">PLoS biology</searchLink> [PLoS Biol] 2026 Apr 16; Vol. 24 (4), pp. e3003765. <i>Date of Electronic Publication: </i>2026 Apr 16 (<i>Print Publication: </i>2026).
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        Value: 10.1371/journal.pbio.3003765
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