Usefulness of an S-1 dosage formula for predicting adverse events in adjuvant chemotherapy for curatively resected pancreatic cancer: an exploratory analysis of the randomized clinical trial (JASPAC-01).

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Title: Usefulness of an S-1 dosage formula for predicting adverse events in adjuvant chemotherapy for curatively resected pancreatic cancer: an exploratory analysis of the randomized clinical trial (JASPAC-01).
Authors: Ishigaki K; Department of Clinical Oncology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan. ishigakikazunaga@gmail.com.; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. ishigakikazunaga@gmail.com., Nakai Y; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Department of Internal Medicine, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan., Kashiwabara K; Data Science Office, Clinical Research Promotion Center, The University of Tokyo Hospital, Tokyo, Japan., Fujishiro M; Department of Clinical Oncology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Gotohda N; Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital East, Kashiwa, Japan., Toyama H; Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan., Maeda A; Department of Surgery, Ogaki Municipal Hospital, Ogaki, Japan., Shimizu Y; Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan., Miyamoto A; Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan., Takahashi A; Department of Gastrointestinal Surgery, Saitama Cancer Center, Saitama, Japan., Morinaga S; Department of Hepato-Biliary and Pancreatic Surgery, Kanagawa Cancer Center, Yokohama, Japan., Yanagibashi H; Division of Hepato-Biliary-Pancreatic Surgery, Chiba Cancer Center, Chiba, Japan., Goto T; Division of Gastroenterology, Department of Internal Medicine, Asahikawa Medical University, Asahikawa, Japan., Sakuma Y; Division of Gastroenterological, General, and Transplant Surgery, Department of Surgery, Jichi Medical University, Shimotsuke, Japan., Tomikawa M; Department of Hepato-Biliary-Pancreatic Surgery, Tochigi Cancer Center, Utsunomiya, Japan., Ojima H; Gunma Prefectural Cancer Center Department of Gastroenterological Surgery, Ota, Japan., Okamura Y; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan., Fukutomi A; Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Shizuoka, Japan., Boku N; Department of Oncology and General Medicine, IMSUT Hospital, Institute of Medical Science, University of Tokyo, Bunkyo-ku, Japan., Uesaka K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Source: Journal of gastroenterology [J Gastroenterol] 2026 Jun; Vol. 61 (6), pp. 821-830. Date of Electronic Publication: 2026 Apr 17.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Springer International Country of Publication: Japan NLM ID: 9430794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-5922 (Electronic) Linking ISSN: 09441174 NLM ISO Abbreviation: J Gastroenterol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1435-5922
DOI:10.1007/s00535-026-02413-5