Usefulness of an S-1 dosage formula for predicting adverse events in adjuvant chemotherapy for curatively resected pancreatic cancer: an exploratory analysis of the randomized clinical trial (JASPAC-01).

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Title: Usefulness of an S-1 dosage formula for predicting adverse events in adjuvant chemotherapy for curatively resected pancreatic cancer: an exploratory analysis of the randomized clinical trial (JASPAC-01).
Authors: Ishigaki K; Department of Clinical Oncology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan. ishigakikazunaga@gmail.com.; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. ishigakikazunaga@gmail.com., Nakai Y; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Department of Internal Medicine, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan., Kashiwabara K; Data Science Office, Clinical Research Promotion Center, The University of Tokyo Hospital, Tokyo, Japan., Fujishiro M; Department of Clinical Oncology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Gotohda N; Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital East, Kashiwa, Japan., Toyama H; Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan., Maeda A; Department of Surgery, Ogaki Municipal Hospital, Ogaki, Japan., Shimizu Y; Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan., Miyamoto A; Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan., Takahashi A; Department of Gastrointestinal Surgery, Saitama Cancer Center, Saitama, Japan., Morinaga S; Department of Hepato-Biliary and Pancreatic Surgery, Kanagawa Cancer Center, Yokohama, Japan., Yanagibashi H; Division of Hepato-Biliary-Pancreatic Surgery, Chiba Cancer Center, Chiba, Japan., Goto T; Division of Gastroenterology, Department of Internal Medicine, Asahikawa Medical University, Asahikawa, Japan., Sakuma Y; Division of Gastroenterological, General, and Transplant Surgery, Department of Surgery, Jichi Medical University, Shimotsuke, Japan., Tomikawa M; Department of Hepato-Biliary-Pancreatic Surgery, Tochigi Cancer Center, Utsunomiya, Japan., Ojima H; Gunma Prefectural Cancer Center Department of Gastroenterological Surgery, Ota, Japan., Okamura Y; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan., Fukutomi A; Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Shizuoka, Japan., Boku N; Department of Oncology and General Medicine, IMSUT Hospital, Institute of Medical Science, University of Tokyo, Bunkyo-ku, Japan., Uesaka K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Source: Journal of gastroenterology [J Gastroenterol] 2026 Jun; Vol. 61 (6), pp. 821-830. Date of Electronic Publication: 2026 Apr 17.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Springer International Country of Publication: Japan NLM ID: 9430794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-5922 (Electronic) Linking ISSN: 09441174 NLM ISO Abbreviation: J Gastroenterol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Usefulness of an S-1 dosage formula for predicting adverse events in adjuvant chemotherapy for curatively resected pancreatic cancer: an exploratory analysis of the randomized clinical trial (JASPAC-01).
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  Data: <searchLink fieldCode="AU" term="%22Ishigaki+K%22">Ishigaki K</searchLink>; Department of Clinical Oncology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan. ishigakikazunaga@gmail.com.; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. ishigakikazunaga@gmail.com.<br /><searchLink fieldCode="AU" term="%22Nakai+Y%22">Nakai Y</searchLink>; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Department of Internal Medicine, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kashiwabara+K%22">Kashiwabara K</searchLink>; Data Science Office, Clinical Research Promotion Center, The University of Tokyo Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Fujishiro+M%22">Fujishiro M</searchLink>; Department of Clinical Oncology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Gotohda+N%22">Gotohda N</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital East, Kashiwa, Japan.<br /><searchLink fieldCode="AU" term="%22Toyama+H%22">Toyama H</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Maeda+A%22">Maeda A</searchLink>; Department of Surgery, Ogaki Municipal Hospital, Ogaki, Japan.<br /><searchLink fieldCode="AU" term="%22Shimizu+Y%22">Shimizu Y</searchLink>; Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Miyamoto+A%22">Miyamoto A</searchLink>; Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+A%22">Takahashi A</searchLink>; Department of Gastrointestinal Surgery, Saitama Cancer Center, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Morinaga+S%22">Morinaga S</searchLink>; Department of Hepato-Biliary and Pancreatic Surgery, Kanagawa Cancer Center, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Yanagibashi+H%22">Yanagibashi H</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery, Chiba Cancer Center, Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Goto+T%22">Goto T</searchLink>; Division of Gastroenterology, Department of Internal Medicine, Asahikawa Medical University, Asahikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Sakuma+Y%22">Sakuma Y</searchLink>; Division of Gastroenterological, General, and Transplant Surgery, Department of Surgery, Jichi Medical University, Shimotsuke, Japan.<br /><searchLink fieldCode="AU" term="%22Tomikawa+M%22">Tomikawa M</searchLink>; Department of Hepato-Biliary-Pancreatic Surgery, Tochigi Cancer Center, Utsunomiya, Japan.<br /><searchLink fieldCode="AU" term="%22Ojima+H%22">Ojima H</searchLink>; Gunma Prefectural Cancer Center Department of Gastroenterological Surgery, Ota, Japan.<br /><searchLink fieldCode="AU" term="%22Okamura+Y%22">Okamura Y</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Fukutomi+A%22">Fukutomi A</searchLink>; Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Boku+N%22">Boku N</searchLink>; Department of Oncology and General Medicine, IMSUT Hospital, Institute of Medical Science, University of Tokyo, Bunkyo-ku, Japan.<br /><searchLink fieldCode="AU" term="%22Uesaka+K%22">Uesaka K</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
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  Data: <searchLink fieldCode="JN" term="%229430794%22">Journal of gastroenterology</searchLink> [J Gastroenterol] 2026 Jun; Vol. 61 (6), pp. 821-830. <i>Date of Electronic Publication: </i>2026 Apr 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International%22">Springer International </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>9430794 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1435-5922 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209441174%22">09441174 </searchLink><i>NLM ISO Abbreviation: </i>J Gastroenterol <i>Subsets: </i>MEDLINE
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