EYA4 promotes cellular senescence by enhancing P21 transcription through interaction with SIX2.
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| Title: | EYA4 promotes cellular senescence by enhancing P21 transcription through interaction with SIX2. |
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| Authors: | Li X; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-Sen University, Guangzhou, Guangdong, 510275, People's Republic of China., Mao P; Institute for Cancer Medicine, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, People's Republic of China., Chen D; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-Sen University, Guangzhou, Guangdong, 510275, People's Republic of China., Li L; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-Sen University, Guangzhou, Guangdong, 510275, People's Republic of China., Fang H; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-Sen University, Guangzhou, Guangdong, 510275, People's Republic of China., Huang J; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-Sen University, Guangzhou, Guangdong, 510275, People's Republic of China., Liu H; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-Sen University, Guangzhou, Guangdong, 510275, People's Republic of China. liuhy5@mail.sysu.edu.cn. |
| Source: | Advanced biotechnology [Adv Biotechnol (Singap)] 2026 Apr 17; Vol. 4 (2). Date of Electronic Publication: 2026 Apr 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Singapore Country of Publication: Singapore NLM ID: 9918821788106676 Publication Model: Electronic Cited Medium: Internet ISSN: 2948-2801 (Electronic) Linking ISSN: 29482801 NLM ISO Abbreviation: Adv Biotechnol (Singap) Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2948-2801 |
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| DOI: | 10.1007/s44307-026-00109-8 |
