Discovery of an Endonuclease G-inhibitory Ku80-peptide protecting against leukemogenic rearrangements at the MLL breakpoint cluster.
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| Title: | Discovery of an Endonuclease G-inhibitory Ku80-peptide protecting against leukemogenic rearrangements at the MLL breakpoint cluster. |
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| Authors: | Eberle J; Department of Obstetrics and Gynecology, Ulm University, Ulm, Germany., Salem A; Department of Obstetrics and Gynecology, Ulm University, Ulm, Germany., Hofmann M; Department of Physics, Institute of Biophysics, Ulm University, Ulm, Germany.; Department of Physics, Institute of Experimental Physics, Ulm University, Ulm, Germany., Reisser A; Department of Physics, Institute of Biophysics, Ulm University, Ulm, Germany., Ruiz-Blanco YB; Department of Biology, Computational Biochemistry, University of Duisburg-Essen, Essen, Germany., Almeida-Hernandez Y; Department of Biochemical and Chemical Engineering, Chair of Computational Bioengineering, Technical University Dortmund, Dortmund, Germany., Gole B; Department of Obstetrics and Gynecology, Ulm University, Ulm, Germany.; Centre for human molecular genetics and pharmacogenomics, Faculty of Medicine, University of Maribor, SI, Maribor, Slovenia., Rall-Scharpf M; Department of Obstetrics and Gynecology, Ulm University, Ulm, Germany., Angulo-Capel J; Department of Physics, Institute of Biophysics, Ulm University, Ulm, Germany.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 149-153, Barcelona, Spain., Monecke T; Institute of Pharmaceutical Biotechnology, Ulm University, James-Franck-Ring N27, Ulm, Germany., Sanchez-Garcia E; Department of Biology, Computational Biochemistry, University of Duisburg-Essen, Essen, Germany. elsa.sanchez@tu-dortmund.de.; Department of Biochemical and Chemical Engineering, Chair of Computational Bioengineering, Technical University Dortmund, Dortmund, Germany. elsa.sanchez@tu-dortmund.de., Gebhardt JCM; Department of Physics, Institute of Biophysics, Ulm University, Ulm, Germany. christof.gebhardt@uni-ulm.de.; Department of Physics, Institute of Experimental Physics, Ulm University, Ulm, Germany. christof.gebhardt@uni-ulm.de., Wiesmüller L; Department of Obstetrics and Gynecology, Ulm University, Ulm, Germany. lisa.wiesmueller@uni-ulm.de. |
| Source: | Nature communications [Nat Commun] 2026 Apr 17; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-026-72034-2 |