NAT10 promotes gallbladder cancer progression by remodeling cholesterol metabolism via PCSK9 mRNA acetylation.
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| Title: | NAT10 promotes gallbladder cancer progression by remodeling cholesterol metabolism via PCSK9 mRNA acetylation. |
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| Authors: | Chen ZY; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China., Wang MY; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China., Ma B; Department of Gastrointestinal Surgery, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Zhao C; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China., Pan LJ; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China., Wang ZY; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China., Wang YT; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China., Mao PY; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China., Zhao X; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China., Qin DL; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China., Shu YJ; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China. shuyijun19881125@163.com.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China. shuyijun19881125@163.com., Zhang YJ; Department of Cardio-Thoracic Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. Zyjcpb@126.com., Xiang SS; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China. xiangshanshan1989@163.com.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China. xiangshanshan1989@163.com., Dong P; Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China. dongping@xinhuamed.com.cn.; Shanghai Key Laboratory of Biliary Tract Disease Research, China, Shanghai, China. dongping@xinhuamed.com.cn. |
| Source: | Cell death discovery [Cell Death Discov] 2026 Apr 16; Vol. 12 (1). Date of Electronic Publication: 2026 Apr 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2058-7716 |
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| DOI: | 10.1038/s41420-026-03104-z |
