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Safety and effectiveness of stereotactic radiosurgery for larger hemangioblastomas (>2cc): A multi-center retrospective study.

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Title: Safety and effectiveness of stereotactic radiosurgery for larger hemangioblastomas (>2cc): A multi-center retrospective study.
Authors: Pichardo-Rojas PS; Vivian L. Smith Department of Neurosurgery, University of Texas Health Science Center at Houston, Texas, United States of America., Tos SM; Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, United States of America., Mantziaris G; Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, United States of America., Shaaban A; Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, United States of America., Nabeel AM; Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; Department of Neurological Surgery, Benha University, Qalubya, Egypt., Reda WA; Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; Department of Neurological Surgery, Ain Shams University, Cairo, Egypt., Tawadros SR; Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; Department of Neurological Surgery, Ain Shams University, Cairo, Egypt., AbdelKarim K; Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; Department of Clinical Oncology, Ain Shams University, Cairo, Egypt., El-Shehaby AMN; Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; Department of Neurological Surgery, Ain Shams University, Cairo, Egypt., Emad RM; Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; Department of Radiation Oncology, National Cancer Institute, Cairo University, Cairo, Egypt., Wei Z; Department of Neurological Surgery, University of Pittsburgh medical center, Pittsburgh, Pennsylvania, United States of America., McKendrick LM; Department of Neurological Surgery, University of Pittsburgh medical center, Pittsburgh, Pennsylvania, United States of America., Niranjan A; Department of Neurological Surgery, University of Pittsburgh medical center, Pittsburgh, Pennsylvania, United States of America., Lunsford LD; Department of Neurological Surgery, University of Pittsburgh medical center, Pittsburgh, Pennsylvania, United States of America., Peker S; Department of Neurological Surgery, Koc University School of Medicine, Istanbul, Turkey., Samanci Y; Department of Neurological Surgery, Koc University School of Medicine, Istanbul, Turkey., Liscak R; Department of Stereotactic and Radiation Neurosurgery, Na Homolce Hospital, Prague, Czech Republic., May J; Department of Stereotactic and Radiation Neurosurgery, Na Homolce Hospital, Prague, Czech Republic., Mathieu D; Department of Neurological Surgery, Université de Sherbrooke, Centre de recherche du CHUS, Canada., Lee CC; Department of Neurological Surgery, Neurological Institute, Taipei Veteran General Hospital, Taipei, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Yang HC; Department of Neurological Surgery, Neurological Institute, Taipei Veteran General Hospital, Taipei, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Dono A; Vivian L. Smith Department of Neurosurgery, University of Texas Health Science Center at Houston, Texas, United States of America., Blanco AI; Vivian L. Smith Department of Neurosurgery, University of Texas Health Science Center at Houston, Texas, United States of America., Esquenazi Y; Vivian L. Smith Department of Neurosurgery, University of Texas Health Science Center at Houston, Texas, United States of America., Moreno NM; Radiosurgery Unit, Hospital Ruber Internacional, Madrid, Spain., Álvarez RM; Radiosurgery Unit, Hospital Ruber Internacional, Madrid, Spain., Picozzi P; Department of Neurological Surgery, IRCCS Humanitas Research Hospital, Milan, Italy., Franzini A; Department of Neurological Surgery, IRCCS Humanitas Research Hospital, Milan, Italy., Tripathi M; Department of Neurological Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Sumi T; Department of Neurological Surgery, Dokkyo Medical University, Mibu, Tochigi, Japan., Uzuka T; Department of Neurological Surgery, Dokkyo Medical University, Mibu, Tochigi, Japan., Kano H; Department of Neurological Surgery, Dokkyo Medical University, Mibu, Tochigi, Japan., Bailey D; Department of Neurological Surgery, Penn State Health - Hershey Medical Center, Pennsylvania, United States of America., Zacharia BE; Department of Neurological Surgery, Penn State Health - Hershey Medical Center, Pennsylvania, United States of America., Cifarelli CP; Department of Neurological Surgery, West Virginia University, United States of America.; Department of Radiation Oncology, West Virginia University, United States of America., Cifarelli DT; Department of Neurological Surgery, West Virginia University, United States of America., Hack JD; Department of Radiation Oncology, West Virginia University, United States of America., Speckter H; Dominican Gamma Knife Center and Radiology Department, CEDIMAT, Santo Domingo, Dominican Republic., Lazo E; Dominican Gamma Knife Center and Radiology Department, CEDIMAT, Santo Domingo, Dominican Republic., Warnick RE; Gamma Knife Center, Jewish hospital, Mayfield clinic, Cincinnati, Ohio, United States of America., Schoenhals JE; Department of Radiation Oncology, The Ohio State University, Ohio, United States of America., Palmer JD; Department of Radiation Oncology, The Ohio State University, Ohio, United States of America., Xu Z; Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, United States of America., Sheehan JP; Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, United States of America.
Source: PloS one [PLoS One] 2026 Apr 17; Vol. 21 (4), pp. e0337000. Date of Electronic Publication: 2026 Apr 17 (Print Publication: 2026).
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0337000