Associations between early loss of skeletal muscle and osimertinib trough concentrations in patients with advanced EGFR-mutated NSCLC.

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Title: Associations between early loss of skeletal muscle and osimertinib trough concentrations in patients with advanced EGFR-mutated NSCLC.
Authors: Sikkema BJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Dr. Molewaterplein 40, PO Box 2040, Rotterdam, CA 3000, the Netherlands., Veerman M; Department of Pulmonary Medicine, Erasmus MC Cancer Institute, Erasmus University Medical Center, Dr. Molewaterplein 40, PO Box 2040, Rotterdam, CA 3000, the Netherlands., Hoop EO; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Dr. Molewaterplein 40, PO Box 2040, Rotterdam, CA 3000, the Netherlands., Paats MS; Department of Pulmonary Medicine, Erasmus MC Cancer Institute, Erasmus University Medical Center, Dr. Molewaterplein 40, PO Box 2040, Rotterdam, CA 3000, the Netherlands., Mathijssen RHJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Dr. Molewaterplein 40, PO Box 2040, Rotterdam, CA 3000, the Netherlands., Dingemans AC; Department of Pulmonary Medicine, Erasmus MC Cancer Institute, Erasmus University Medical Center, Dr. Molewaterplein 40, PO Box 2040, Rotterdam, CA 3000, the Netherlands. Electronic address: a.dingemans@erasmusmc.nl.
Source: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2026 Jun 03; Vol. 240, pp. 116742. Date of Electronic Publication: 2026 Apr 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0852
DOI:10.1016/j.ejca.2026.116742