Exosomal microRNA-4800-3p in portal vein blood promotes liver metastasis in pancreatic cancer by targeting PLAA.

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Title: Exosomal microRNA-4800-3p in portal vein blood promotes liver metastasis in pancreatic cancer by targeting PLAA.
Authors: Miyahara S; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Takahashi H; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan. htakahashi8@gesurg.med.osaka-u.ac.jp., Tomimaru Y; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Kobayashi S; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Tahara S; Department of Pathology, Graduate School of Medicine, The University of Osaka, 2-2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Sasaki K; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Hasegawa S; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Iwagami Y; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Yamada D; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Akita H; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Asaoka T; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Noda T; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Wada H; Department of Gastroenterological Surgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan., Shimizu J; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Morii E; Department of Pathology, Graduate School of Medicine, The University of Osaka, 2-2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Doki Y; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan., Eguchi H; Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 E2, Yamadaoka, Suita, 565-0871, Osaka, Japan.
Source: Scientific reports [Sci Rep] 2026 Apr 19; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-026-48779-7