Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell-Type-Specific TGFβ Modulators.
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| Title: | Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell-Type-Specific TGFβ Modulators. |
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| Authors: | van Dinther M; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands., Schwartze T; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Zhang J; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands., Fan K; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands., van der Zon G; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands., Power L; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK., Hinck CS; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Ciancia C; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK., Mukundan A; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Gonzalez-Prieto R; Andalusian Center for Molecular Biology and Regenerative Medicine, Universidad de Sevilla - CSIC - Universidad Pablo de Olavide, Sevilla, Spain.; Department of Cell Biology, Faculty of Biology, University of Sevilla, Sevilla, Spain., van Veelen P; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Maizels RM; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK., Hinck AP; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Ten Dijke P; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands. |
| Source: | Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Apr 20, pp. e75322. Date of Electronic Publication: 2026 Apr 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42003773 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell-Type-Specific TGFβ Modulators. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22van+Dinther+M%22">van Dinther M</searchLink>; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schwartze+T%22">Schwartze T</searchLink>; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Fan+K%22">Fan K</searchLink>; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Zon+G%22">van der Zon G</searchLink>; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Power+L%22">Power L</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Hinck+CS%22">Hinck CS</searchLink>; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Ciancia+C%22">Ciancia C</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Mukundan+A%22">Mukundan A</searchLink>; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Prieto+R%22">Gonzalez-Prieto R</searchLink>; Andalusian Center for Molecular Biology and Regenerative Medicine, Universidad de Sevilla - CSIC - Universidad Pablo de Olavide, Sevilla, Spain.; Department of Cell Biology, Faculty of Biology, University of Sevilla, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22van+Veelen+P%22">van Veelen P</searchLink>; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Maizels+RM%22">Maizels RM</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Hinck+AP%22">Hinck AP</searchLink>; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Ten+Dijke+P%22">Ten Dijke P</searchLink>; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101664569%22">Advanced science (Weinheim, Baden-Wurttemberg, Germany)</searchLink> [Adv Sci (Weinh)] 2026 Apr 20, pp. e75322. <i>Date of Electronic Publication: </i>2026 Apr 20. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22WILEY-VCH%22">WILEY-VCH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101664569 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2198-3844 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221983844%22">21983844 </searchLink><i>NLM ISO Abbreviation: </i>Adv Sci (Weinh) <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42003773 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/advs.75322 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e75322 Titles: – TitleFull: Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell-Type-Specific TGFβ Modulators. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: van Dinther M – PersonEntity: Name: NameFull: Schwartze T – PersonEntity: Name: NameFull: Zhang J – PersonEntity: Name: NameFull: Fan K – PersonEntity: Name: NameFull: van der Zon G – PersonEntity: Name: NameFull: Power L – PersonEntity: Name: NameFull: Hinck CS – PersonEntity: Name: NameFull: Ciancia C – PersonEntity: Name: NameFull: Mukundan A – PersonEntity: Name: NameFull: Gonzalez-Prieto R – PersonEntity: Name: NameFull: van Veelen P – PersonEntity: Name: NameFull: Maizels RM – PersonEntity: Name: NameFull: Hinck AP – PersonEntity: Name: NameFull: Ten Dijke P IsPartOfRelationships: – BibEntity: Dates: – D: 20 M: 04 Text: 2026 Apr 20 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2198-3844 Titles: – TitleFull: Advanced science (Weinheim, Baden-Wurttemberg, Germany) Type: main |
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