Implementation of a kidney protection strategy to prevent acute kidney injury after major surgery in high-risk patients identified by biomarkers: a systematic review and individual participant data meta-analysis of randomized controlled trials.

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Title: Implementation of a kidney protection strategy to prevent acute kidney injury after major surgery in high-risk patients identified by biomarkers: a systematic review and individual participant data meta-analysis of randomized controlled trials.
Authors: von Groote T; Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Bormann E; Institute of Biometry and Clinical Research, University of Münster, Münster, Germany., Marcello M; Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.; Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Vicenza, Italy., Tunnicliffe DJ; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia., Göcze I; Department of Surgery and Surgical Intensive Care, University Hospital Regensburg, Regensburg, Germany., Sadjadi M; Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Forni LG; Department of Intensive Care Medicine, Royal Surrey Foundation Hospital Trust, Guildford, Surrey, UK.; School of Medicine, University of Surrey, Guildford, Surrey, UK., Gómez H; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, USA., Kellum JA; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, USA., Zarbock A; Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany. zarbock@uni-muenster.de.
Source: Intensive care medicine [Intensive Care Med] 2026 May; Vol. 52 (5), pp. 1023-1034. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-1238
DOI:10.1007/s00134-026-08399-1