In vivo CAR-cell therapy: current challenges and emerging therapeutic advances.

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Title: In vivo CAR-cell therapy: current challenges and emerging therapeutic advances.
Authors: Yang YM; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Chang-Le Xi Street #169, Xi'an, 710032, China.; Basic Medical College, Fourth Military Medical University, Xi'an, 710032, China., Bao B; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Chang-Le Xi Street #169, Xi'an, 710032, China.; Basic Medical College, Fourth Military Medical University, Xi'an, 710032, China., Cao YH; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Chang-Le Xi Street #169, Xi'an, 710032, China.; Basic Medical College, Fourth Military Medical University, Xi'an, 710032, China., Yao J; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Chang-Le Xi Street #169, Xi'an, 710032, China., Ding YF; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Chang-Le Xi Street #169, Xi'an, 710032, China., Hu YY; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Chang-Le Xi Street #169, Xi'an, 710032, China., Fan F; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Chang-Le Xi Street #169, Xi'an, 710032, China. casdial@live.com., Zhao JL; State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Chang-Le Xi Street #169, Xi'an, 710032, China. zhaojl@fmmu.edu.cn.
Source: Molecular biomedicine [Mol Biomed] 2026 Apr 20; Vol. 7 (1). Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 9918283581406676 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-8651 (Electronic) Linking ISSN: 26628651 NLM ISO Abbreviation: Mol Biomed Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2662-8651
DOI:10.1186/s43556-026-00447-y