SMARCA4 activation engages FOSL1 to drive enhancer reprogramming and tumorigenic phenotypes in SMARCA4-deficient LUAD cells.
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| Title: | SMARCA4 activation engages FOSL1 to drive enhancer reprogramming and tumorigenic phenotypes in SMARCA4-deficient LUAD cells. |
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| Authors: | Yang HJ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea.; Cancer Genomics Research Laboratory, Cancer Research Institute, Seoul National University, Seoul, Republic of Korea., Kim EJ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea.; Cancer Genomics Research Laboratory, Cancer Research Institute, Seoul National University, Seoul, Republic of Korea., Kim S; State University of New York Upstate Medical University, Syracuse, NY, USA., Song SH; Cancer Genomics Research Laboratory, Cancer Research Institute, Seoul National University, Seoul, Republic of Korea., Kim TY; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea. kimty@snu.ac.kr.; Cancer Genomics Research Laboratory, Cancer Research Institute, Seoul National University, Seoul, Republic of Korea. kimty@snu.ac.kr.; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea. kimty@snu.ac.kr. |
| Source: | Cell death discovery [Cell Death Discov] 2026 Apr 20; Vol. 12 (1). Date of Electronic Publication: 2026 Apr 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2058-7716 |
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| DOI: | 10.1038/s41420-026-03100-3 |