Bispecific Ligand-Based EphB4 CAR-T Cells Generated Using Ephrin-B2 Show Potent Antitumor Activity Against Lung Adenocarcinoma.
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| Title: | Bispecific Ligand-Based EphB4 CAR-T Cells Generated Using Ephrin-B2 Show Potent Antitumor Activity Against Lung Adenocarcinoma. |
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| Authors: | Kumeda H; Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan., Hirabayashi K; Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan., Mishima S; Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan., Morita K; Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan., Furui Y; Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan., Fujioka M; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, Matsumoto, Japan., Nakajima T; Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan., Tanaka M; Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.; Center for Advanced Research of Gene and Cell Therapy in Shinshu University (CARS), Shinshu University School of Medicine, Matsumoto, Japan.; A-SEEDS Co., Ltd., Matsumoto, Japan., Sato Y; Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan., Uehara T; Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan., Yagyu S; Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.; Center for Advanced Research of Gene and Cell Therapy in Shinshu University (CARS), Shinshu University School of Medicine, Matsumoto, Japan.; A-SEEDS Co., Ltd., Matsumoto, Japan., Shimizu K; Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan., Nakazawa Y; Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.; Center for Advanced Research of Gene and Cell Therapy in Shinshu University (CARS), Shinshu University School of Medicine, Matsumoto, Japan.; A-SEEDS Co., Ltd., Matsumoto, Japan. |
| Source: | Cancer science [Cancer Sci] 2026 Jun; Vol. 117 (6), pp. 1724-1735. Date of Electronic Publication: 2026 Apr 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1349-7006 |
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| DOI: | 10.1111/cas.70397 |
