On-treatment viral factors affect subsequent hepatitis B surface antigen seroclearance in patients treated with nucleos(t)ide analogs for > 10 years.

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Title: On-treatment viral factors affect subsequent hepatitis B surface antigen seroclearance in patients treated with nucleos(t)ide analogs for > 10 years.
Authors: Hosaka T; Department of Gastroenterology and Hepatology, The University of Osaka Graduate School of Medicine, Suita, Japan.; Department of Hepatology, Toranomon Hospital, Tokyo, Japan., Hikita H; Department of Gastroenterology and Hepatology, The University of Osaka Graduate School of Medicine, Suita, Japan. hikita@gh.med.osaka-u.ac.jp., Tahata Y; Department of Gastroenterology and Hepatology, The University of Osaka Graduate School of Medicine, Suita, Japan., Yamada R; Department of Gastroenterology and Hepatology, The University of Osaka Graduate School of Medicine, Suita, Japan., Murai K; Department of Gastroenterology and Hepatology, The University of Osaka Graduate School of Medicine, Suita, Japan., Miyazaki M; Department of Gastroenterology, Osaka Keisatsu Hospital, Osaka, Japan., Ishida H; Department of Gastroenterology and Hepatology, Ikeda Municipal Hospital, Ikeda, Japan., Hosui A; Department of Gastroenterology and Hepatology, Osaka Rosai Hospital, Sakai, Japan., Sakamori R; Department of Gastroenterology and Hepatology, NHO Osaka National Hospital, Osaka, Japan., Tatsumi N; Department of Gastroenterology and Hepatology, Japan Community Healthcare Organization Osaka Hospital, Osaka, Japan., Doi Y; Department of Gastroenterology and Hepatology, Otemae Hospital, Osaka, Japan., Ohkawa K; Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan., Egawa S; Department of Gastroenterology and Hepatology, Kinki Central Hospital of Mutual Aid Association of Public School Teachers, Itami, Japan., Nawa T; Department of Gastroenterology and Hepatology, Higashiosaka City Medical Center, Osaka, Japan., Nozaki Y; Department of Gastroenterology and Hepatology, Kansai Rosai Hospital, Amagasaki, Japan., Imanaka K; Department of Gastroenterology and Hepatology, Itami City Hospital, Itami, Japan., Nakahara M; Department of Gastroenterology and Hepatology, Minoh City Hospital, Minoh, Japan., Sakakibara M; Department of Gastroenterology and Hepatology, Yao Municipal Hospital, Yao, Japan., Yakushijin T; Department of Gastroenterology and Hepatology, Osaka General Medical Center, Osaka, Japan., Yoshida Y; Department of Gastroenterology and Hepatology, Suita Municipal Hospital, Suita, Japan., Ogawa H; Department of Gastroenterology, Nishinomiya Municipal Central Hospital, Nishinomiya, Japan., Usui T; Department of Gastroenterology and Hepatology, Ashiya Municipal Hospital, Ashiya, Japan., Matsumoto K; Department of Gastroenterology and Hepatology, Toyonaka Municipal Hospital, Toyonaka, Japan., Maesaka K; Department of Gastroenterology and Hepatology, The University of Osaka Graduate School of Medicine, Suita, Japan., Shirai K; Department of Gastroenterology and Hepatology, The University of Osaka Graduate School of Medicine, Suita, Japan., Makino Y; Department of Gastroenterology and Hepatology, The University of Osaka Graduate School of Medicine, Suita, Japan., Saito Y; Department of Gastroenterology and Hepatology, The University of Osaka Graduate School of Medicine, Suita, Japan., Kodama T; Department of Gastroenterology and Hepatology, The University of Osaka Graduate School of Medicine, Suita, Japan., Takehara T; Department of Gastroenterology and Hepatology, Kansai Rosai Hospital, Amagasaki, Japan.
Source: Journal of gastroenterology [J Gastroenterol] 2026 Jul; Vol. 61 (7), pp. 990-1002. Date of Electronic Publication: 2026 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Country of Publication: Japan NLM ID: 9430794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-5922 (Electronic) Linking ISSN: 09441174 NLM ISO Abbreviation: J Gastroenterol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1435-5922
DOI:10.1007/s00535-026-02415-3