Organ injury in systemic autoimmunity is mediated by stem-like CD8+ T cells arising from tissue-draining lymph nodes.

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Bibliographic Details
Title: Organ injury in systemic autoimmunity is mediated by stem-like CD8+ T cells arising from tissue-draining lymph nodes.
Authors: Al Souz J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA., Wei Y; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06520, USA., Cui C; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA., Qu R; Computational Biology and Bioinformatics Program, Yale University, New Haven, CT 06520, USA., Choi JY; Department of Internal Medicine, Section of Rheumatology, Allergy and Immunology, Yale University School of Medicine, New Haven, CT 06520, USA., Wang F; Department of Internal Medicine, Section of Rheumatology, Allergy and Immunology, Yale University School of Medicine, New Haven, CT 06520, USA., Moioffer SJ; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA., Barrett J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA., Chernova I; Department of Internal Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520, USA., Nadella M; Department of Internal Medicine, Section of Rheumatology, Allergy and Immunology, Yale University School of Medicine, New Haven, CT 06520, USA., Siniscalco ER; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Moeckel G; Department of Pathology, Yale University School of Medicine, New Haven, CT 06520, USA., Joshi NS; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA., Chen PM; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan., Arazi A; Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030, USA., Ho YC; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06520, USA., Craft J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Internal Medicine, Section of Rheumatology, Allergy and Immunology, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: joseph.craft@yale.edu.
Corporate Authors: Accelerating Medicines Partnership: RA/SLE Network
Source: Immunity [Immunity] 2026 Jun 09; Vol. 59 (6), pp. 1667-1687.e15. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4180
DOI:10.1016/j.immuni.2026.03.022